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Tag: DIMEB

May 4, 2023 CD derivatives / Life sciences

Breathtaking anatomical view of a mammalian organism enabled by DIMEB

Science magazine highlights a new method of visualization of organs in such a detail that has never seen before. A

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August 29, 2022 CD as API / Pharma applications

The Effect of Cyclodextrins in Cholesterol and Ganglioside Depletion in Rat Brain Synaptosomes

In this recently published article, the effect of four cyclodextrin derivatives on cholesterol and ganglioside depletion was investigated:  two alpha

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June 10, 2022 Drug delivery / Pharma applications

Biophysical Studies and In Vitro Effects on Tumor Cell Lines of Cannabidiol and Its Cyclodextrin Inclusion Complexes

Phytocannabinoids possess anticancer properties, as established in vitro and in vivo. However, they are characterized by high lipophilicity. To improve

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July 15, 2021 E-ducation

Amorphous Drug Solubility and Maximum Free Drug Concentrations in Cyclodextrin Solutions: A Quantitative Study Using NMR Diffusometry

The effect of CD on the amorphous drug solubility and the maximum thermodynamic activity of the drug in the aqueous

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May 8, 2020 CD derivatives / Drug delivery / Pharma applications

Chlorpromazine complexation with Sugammadex – an extremely high complexation constant

An in press paper on detailed ITC and NMR study of chlorpromazin complexation with various cyclodextrins reports on an unexpected

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November 21, 2019 CD derivatives / Drug delivery

Cyclodextrin-related topics in the latest issue of JIPH

The following cyclodextrin-related papers in  Journal of Inclusion Phenomena and Macrocyclic Chemistry. Volume 95 Number 3-4 might be interesting for the

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January 23, 2019 CD derivatives / Non-pharma applications / Other industrial use / Pharma applications

DIMEB in biotechnology

Heptakis(2,6-di-O-methyl) beta-cyclodextrin is a single isomer with high solubility in cold water, but it crystallizes from water at increased temperatures.

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Recent Posts

  • Environment-Sensitive Fluorophores Report on Structural Organization of Biological Membranes at Various Depths
  • A Cyclodextrin Surprise in a Japanese Supplement
  • Modifying the interior cavity of cyclodextrin
  • Special issue: Novel macrocycles: from synthesis to supramolecular function
  • Chitosan-coated cyclodextrin-based niosomes enable enhanced nose-to-brain delivery of rivastigmine and asiaticoside for Alzheimer’s disease

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Top Posts

  • A Cyclodextrin Surprise in a Japanese Supplement
  • Modifying the interior cavity of cyclodextrin
  • Environment-Sensitive Fluorophores Report on Structural Organization of Biological Membranes at Various Depths
  • Chitosan-coated cyclodextrin-based niosomes enable enhanced nose-to-brain delivery of rivastigmine and asiaticoside for Alzheimer's disease
  • How air fresheners work?
  • HPBCD in an approved non-replicating adenoviral vector-based gene therapy product
  • 22nd International Cyclodextrin Symposium (ICS-22) in India
  • FDA Grants Approval to HPBCD-Enhanced Biologic: A 'Super-Originator' Formulation
  • New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies

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