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Tag: Clinical trial

June 25, 2026 CD derivatives / Drug delivery / Pharma applications

Poly-CD-PEG-camptothecin Combined with Olaparib  in People With Relapsed/​Refractory Small Cell Lung Cancer (Clinical trial)

The authors hypothesized that integrating tumor-targeted topoisomerase I inhibitor delivery with optimized PARP inhibitor scheduling could enable effective combination therapy

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May 7, 2026 CD as API / Pharma applications / Uncategorized

Sugammadex vs Neostigmine: Effects on Obese Patients’ Recovery

Compared with neostigmine, sugammadex promotes faster neuromuscular recovery, but its impact on diaphragmatic function and respiratory recovery in the morbidly

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March 25, 2026 CD derivatives / Drug delivery / Pharma applications

Cantrixil: Advancing a Molecule’s Career with a Cyclodextrin Carrier

The success story of Cantrixil, a potent anti-cancer drug candidate, has been followed on our blog for years, and now

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March 24, 2026 Drug delivery / Pharma applications

Oculis: eye drops with Dexamethasone/gamma-CD complex Phase 3 study concluded soon

Oculis’s most advanced product candidate, OCS-01, is currently in Phase 3 development and aims to be the first eye drop

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January 19, 2026 CD as API / Pharma applications

Sugammadex vs. Neostigmine Reversal After Thoracoscopic Thymectomy in Myasthenia Gravis

Rapid and complete reversal of residual neuromuscular blockade (rNMB) is essential for safe postoperative recovery in patients with myasthenia gravis

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September 22, 2025 CD as API / Pharma applications

7 of 9 patients showed stabilization or improvement: preliminary data from ongoing Phase 3 TransportNPC™ clinical trial

Rafael Holdings, Inc. announced that data from Cyclo Therapeutics’ Phase 3 TransportNPC™ open-label, single-arm sub-study evaluating Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin) for Niemann-Pick

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September 16, 2025 CD as API / Drug delivery / Pharma applications

Cyclodextrin-based therapeutics delivery systems: A review of current clinical trials

Cyclodextrins (CDs) and their polymers are gaining momentum as advanced drug delivery systems. A recent review (https://www.sciencedirect.com/science/article/pii/S2590257125000203) highlights their progress

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January 14, 2025 CD as API / Pharma applications

Cyclodextrin derivative developed by Cyclarity in clinical trial

Cyclarity Therapeutics is pleased to announce regulatory approval to begin its first-in-human clinical trial. The trial will be conducted at CMAX,

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December 11, 2024 CD as API / Pharma applications

Alzheimer’s disease drug development pipeline: 2024

New therapies to prevent or delay the onset of symptoms, slow progression, or improve cognitive and behavioral symptoms of Alzheimer’s

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white hospital beds
September 25, 2024 CD derivatives / Drug delivery / Pharma applications

Merck is about to perform post-marketing safety study of HPBCD-containing PREVYMIS™ injection

Merck Sharp and Dohme LLC. has received initial U.S. Approval: 2017 PREVYMIS™ (letermovir) injection, for intravenous use. In the first

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  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
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  • Adsorption of PFAS to Cationic β-Cyclodextrin Polymers
  • A cyclodextrin polymer that could change the future of batteries
  • Virus-Mediated Self-Assembly of Functional Cyclodextrins for Antiviral Inhibition

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Top Posts

  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
  • BCD in starch-based composite active sheets for the preservation and packaging of blueberry fresh fruit
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Reinforced double-threaded slide-ring networks for accelerated hydrogel discovery and 3D printing
  • Cyclodextrin scientist ranked among the Best Chemistry Scientists of the World
  • Wasabi's bioactive component 6-MSITC formulated with alfa-cyclodextrin improved memory proven in clinical trial.
  • Adsorption of PFAS to Cationic β-Cyclodextrin Polymers
  • Paul Janssen was born 100 years ago
  • Cothreading of Unmodified and Monoazidated β-Mixed cyclodextrins in polyrotaxanes for Niemann Pick disease
  • Alpha-cyclodextrin increases glucagon-like peptide-1 secretion in multiple models and improves metabolic status in mice

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