Poly-β-Cyclodextrin as a Superior Host for Gemcitabine
Gemcitabine remains a vital chemotherapeutic agent, yet its rapid deamination and short systemic persistence necessitate improved delivery strategies. This study
Tag: cyclodextrin polymer
Poly-CD-PEG-camptothecin Combined with Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer (Clinical trial)
The authors hypothesized that integrating tumor-targeted topoisomerase I inhibitor delivery with optimized PARP inhibitor scheduling could enable effective combination therapy
PEG-β-Cyclodextrin polymer-based formulation to increase the antiangiogenic activity of rutin in vivo
Rutin (RTN) is a natural flavonoid with well-documented anti-angiogenic, antioxidant, anti-inflammatory, and anti-cancer properties. However, its therapeutic potential is limited
Sustainable capture and photocatalytic degradation of organic pollutants by high-swelling cyclodextrin polymer loaded with TiO2 nanoparticles
Photocatalytic degradation provides a promising sustainable solution for water purification, but its effectiveness is often limited by the low utilization
Cyclodextrin Polymer Complexation Improves the Tolerability of Parenteral Oestradiol
This study investigates the PEG‑β‑CD polymer, a water‑soluble polyethylene glycol–β‑cyclodextrin cross‑linked carrier, as a potential alternative to conventional oestradiol formulations
Poly(β-cyclodextrin)-coated dysprosium-doped ZnS nanocarriers
This study provides a comprehensive analysis of the structures and properties of zinc sulfide (ZnS) and dysprosium-doped ZnS nanoparticles (NPs)
A water-soluble β-cyclodextrin polymer reduces cholesterol accumulation and autophagy dysfunction in vitro and in Niemann-Pick type C disease model mice
A β-CDP (CycloLab) was used for the experiments. The purity of the β-CDP was >95 %. The β-CDP contained <1 % of
Dual activity of low-molecular-weight polymeric β-cyclodextrins against tuberculosis
/The biological properties of pβCD of different molecular weights were studied. Strikingly, only the low-molecular-weight pβCD (LMW-pβCD) displayed antibacterial activity,
High-swelling cyclodextrin polymer for sustainable water purification
A high-swelling cyclodextrin polymer (His-CDP) is reported that is facilely synthesized without additional design and templates, to achieve high affinity,
A β-cyclodextrin polymer reduces cholesterol accumulation and mitigates autophagy dysfunction in vitro and in a Niemann–Pick Type C animal model
Niemann–Pick disease type C (NPC) and Alzheimer’s disease (AD) are both characterised by cognitive decline and neurological impairment. In each