Enhancing Remdesivir Delivery: PJL Micelles vs SBECD Formulations
Remdesivir (REM), a nucleoside analogue that has been approved for SARS-CoV-2 treatment, is poorly soluble in water and is currently
Tag: SBECD
Cyclodextrin-Based Formulations to Improve Solubility of Poorly Soluble Drugs
This chapter offers a detailed overview of the structural features, different types, and chemical modifications of CDs and their derivatives,
Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
Fungal keratitis (FK) is a leading cause of corneal blindness worldwide. Although voriconazole (VOR) is effective, its poor corneal permeability
Nano-Enabled Toxicity of Pharmaceutical Excipients
Nanotechnology has brought revolutionary advances in the pharmaceutical field. Among drug delivery systems, nanocarriers, which enhance the solubility, stability and
Methyl salicylate/methyl-β-cyclodextrin inclusion complex modulates plant defense against cold and heat stress
Methyl salicylate (MeSA), a known defense modulator, holds promise as a biostimulant; however, its volatility and poor aqueous solubility limit
Cyclodextrin complexation of selected tyrosine kinase inhibitors
The comprehensive physicochemical characterization and cyclodextrin complexation of four tyrosine kinase inhibitors — erlotinib, gefitinib, vandetanib, and lapatinib — were
Improving Drug Bioavailability with Cyclodextrin Complexes: An integrative meta-modeling approach
This study integrates molecular modeling and meta-analysis to evaluate the pharmacokinetic performance and molecular stability of various cyclodextrin-drug systems. A
Continuous chiral CPC in practice: Process intensification for voriconazole enantioseparation
A recent study from RotaChrom Technologies shows that continuous chiral separation by centrifugal partition chromatography (CPC) can be achieved for
Evaluation of the Potential Therapeutic Effects of HPβCD and SBEβCD in a Mouse Model of Acute Ulcerative Colitis
A Nanjing, China based research group designed a tailored investigation [1] based on a surprising previous study [2]. In they
New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA
VYKOURA is a newly approved medication (marketing start date: 02/03/2026) containing leucovorin calcium, a prescription injectable drug used in hospital