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Tag: SBECD

January 18, 2023 CD derivatives / Drug delivery / Pharma applications

New US patent for SBECD purification by CycloLab

The status of US patent application 17/344,217 (“Purification of sulfobutylated cyclodextrins with specific ion exchange resins” by CycloLab, Hungary) was

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January 4, 2023 Drug delivery / Pharma applications

Case Report: Severe SARS-CoV-2 Infection Treated with Remdesivir in a Patient with ESRD

Remdesivir has emerged as a promising antiviral drug against SARS-CoV-2. However, data regarding the clinical benefits of remdesivir in patients

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December 29, 2022 Food / Non-pharma applications

SBECD in food and food packaging

A multifunctional food packaging material (G-Eug-NPs-NF) based on gelatin nanofiber membranes (G-NF) containing eugenol nanoparticles (Eug-NPs) were prepared [1]. The

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December 9, 2022 Drug delivery / Pharma applications

Oil-free eye drops containing Cyclosporine A/SBECD/PVA supramolecular complex

According to the global mapping of dry eye disease (DED), nearly 5 to 50 % of people suffer from DED,

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December 8, 2022 CD derivatives / Drug delivery / Pharma applications

SBECD polymer to prolong the antibacterial activity

SBECD polymer was prepared by crosslinking with 1,6-hexamethylene diisocyanate. Iin vitro studies were conducted on two Escherichia coli strains that differed in

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December 7, 2022 Drug delivery / Pharma applications

An Updated Overview of Cyclodextrin-Based Drug Delivery Systems for Cancer Therapy

Cyclodextrins (CDs) attracted increasing interest over the past few years, leading to the emergence of promising anti-tumor nanomedicines. Tackling their

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November 3, 2022 Drug delivery / Pharma applications

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin: stabilization of supersaturated solution by changing pH from 1.7 to 3.5

In terms of solubilization effect, it was found that phase solubility of RDV increased significantly from intrinsic 1.7 mmol/L at

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October 28, 2022 Drug delivery / Pharma applications

Impact of Remdesivir on SARS-CoV-2 Clearance in a Real-Life Setting: A Matched-Cohort Study

There were 648 patients enrolled in the study (216 cases and 432 controls). Viral clearance (VC) was observed in 490

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October 26, 2022 Drug delivery / Pharma applications

Pharmacokinetic study of sulfobutylether beta-cyclodextrin as an excipient of remdesivir

SBECD (Captisol®) with an average degree of substitution of 6.5 sulfobutylether functional groups (SBE = 6.5), is a solubility enhancer

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September 22, 2022 Drug delivery / Events / Pharma applications

Inaugural Lecture of Prof. Szente at the Hungarian Academy of Sciences

Lajos Szente, Ph.D., D.Sc., one of the founders and former CEO (now Scientific Advisor) of CycloLab at the company and

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