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Category: Supramolecular systems

May 25, 2023 Supramolecular systems

Exploring Isomerism in Isolated Cyclodextrin Oligomers through Trapped Ion Mobility Mass Spectrometry

Cyclodextrin (CD) macrocycles are used to create a wide range of supramolecular architectures which are also of interest in applications

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March 31, 2023 Drug delivery / Pharma applications / Supramolecular systems

Nitric Oxide-Releasing Topological Supramolecular Nanocarriers with sliding CD units against MRSA

Polymeric systems that provide cationic charges or biocide-release therapeutics are used to treat the bacteria-infected wound. However, most antibacterial polymers

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October 14, 2022 Drug delivery / Pharma applications / Supramolecular systems

Stimuli-responsive cyclodextrin-based supramolecular assemblies as drug carriers

In this review with 169 references, the recent advances in stimuli-responsive supramolecular assemblies based on the host–guest chemistry of CDs

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October 7, 2022 CD as API / Pharma applications / Supramolecular systems

Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis

A promising therapy for atherosclerosis treatment was designed by targeting LXR receptor (LXR) on atherosclerotic macrophage, where LXR activation could

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September 27, 2022 CD derivatives / Drug delivery / Pharma applications / Supramolecular systems

Advances in the development of cyclodextrin-based nanogels/microgels for biomedical applications: Drug delivery and beyond

Nanogels/microgels are swollen cross-linked polymer networks with tunable physicochemical properties and are commonly employed for the effective delivery of hydrophilic

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September 21, 2022 Pharma applications / Supramolecular systems

Lipid-based artificial motors – liposome movements via cholesterol extraction

In this work, it is demonstrated that liposome active motion takes advantage of mainly a pair of intrinsic material properties

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September 20, 2022 CD derivatives / Drug delivery / Life sciences / Supramolecular systems

New US patent application on ternary CD/small guest molecule/protein interactions

Cyclolab Ltd filed a patent application (US20220282001) on cyclodextrin containing physical mixtures and inclusion complexes that show improved protein stabilizing

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July 22, 2022 Pharma applications / Supramolecular systems

Antidote-like Effect of Cyclodextrins on Plant Neurotoxin Veratridine

Veratridine (VTD) is a plant neurotoxin that acts by blocking the voltage-gated sodium channels (VGSC) of cell membranes. Symptoms of

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June 27, 2022 CD derivatives / Gene delivery / Supramolecular systems

Matthieu SOLLOGOUB at ICS 20

Matthieu Sollogoub, professor of Biological and Supramolecular Glycochemistry at Sorbonne University gave a plenary lecture at the 20th International Cyclodextrin

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March 24, 2022 CD as API / CD derivatives / Pharma applications / Supramolecular systems

Antidote-like effect of SBECD of plant neurotoxin veratridine on neuro-2a cell viability

A research team consisting of scientists located in Spain and Denmark have successfully proven that the formation of inclusion complexes

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  • The mechanism and therapy of aortic aneurysms
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  • A review on Sulfobutylether-β-cyclodextrin for drug delivery applications

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  • The mechanism and therapy of aortic aneurysms
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  • Crystallization inhibition by methylated cyclodextrin
  • Green materials with promising applications: Cyclodextrins-based deep eutectic supramolecular polymers
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  • Pharmacokinetic studies of hyperoside-2-hydroxypropyl-β-cyclodextrin inclusion complex and ameliorated colitis in mice
  • Aggregation versus inclusion complexes to solubilize drugs with cyclodextrins. A case study using sulfobutylether-β-cyclodextrins and remdesivir

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