Monosubstituted Maltosyl Cyclodextrins for the Potential Treatment of NPC
Niemann-Pick type C is a sever lysosomal storage disease, commonly refereed as ‘children’s Alzheimer’. There is no cure for it
Tag: HPBCD
MIT scientists filed patent for HPBCD treatment in Alzheimer’s disease
Li-Huei Tsai, director of Picower Institute for Learning and Memory (Massachusetts Institute of Technology) and her coworkers recently filed a patent
Inaugural Lecture of Prof. Szente at the Hungarian Academy of Sciences
Lajos Szente, Ph.D., D.Sc., one of the founders and former CEO (now Scientific Advisor) of CycloLab at the company and
Lanosterol eye drops for cataract treatment
HPBCD was found to deliver lanosterol (a tetracyclic triterpenoid) active substance into the crystalline lens of the eye. This delivery
Ozonized HPBCDs as novel materials with oxidative and bactericidal properties
Ozonized (2-Hydroxypropyl)-β-cyclodextrins (Oz-HPbCDs) were produced by direct gas/solid reaction between gaseous ozone (O3) and solid HPbCD. The solid materials obtained
Safety, Immunogenicity of a Novel HPBCD-Adjuvanted Influenza Vaccine
A novel quadrivalent seasonal influenza vaccine (FluCyd-vac) adjuvanted with hydroxypropropyl-b-cyclodextrin (HP-β-CD) was found to be safe and immunogenic despite containing
Chewable formulations – recent reviews
Since their introduction, chewable dosage forms have gained traction due to their ability to facilitate swallowing, especially in paediatric, geriatric
The Effect of Cyclodextrins in Cholesterol and Ganglioside Depletion in Rat Brain Synaptosomes
In this recently published article, the effect of four cyclodextrin derivatives on cholesterol and ganglioside depletion was investigated: two alpha
Cyclodextrin-based delivery systems in parenteral formulations: A critical update review
Amongst all the strategies that can be useful in the development of parenteral formulations, the formation of water-soluble host-guest inclusion
Hot-melt extrusion for cyclodextrin inclusion complex of a multicomponent natural product
This study aimed to investigate whether hot-melt extrusion (HME) processing can promote molecular encapsulation of a multi-component natural product composed