The mechanism and therapy of aortic aneurysms
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally asymptomatic, it poses a significant
Tag: HPBCD
Pharmacokinetic studies of hyperoside-2-hydroxypropyl-β-cyclodextrin inclusion complex and ameliorated colitis in mice
The pharmacokinetic characteristics of Hyperoside-2-hydroxypropyl-β-cyclodextrin inclusion complex in rats were evaluated. Compared with Hyperoside, the results showed that maximum plasma concentration and
Antifungal pentachloronitrobenzene/hydroxypropyl-beta-cyclodextrin inclusion complex nanofibers by electrospinning with no polymer
Pentachloronitrobenzene (PCNB) is an organochlorine protective fungicide with poor water solubility. In this research, pentachloronitrobenzene/hydroxypropyl-β-cyclodextrin inclusion complex nanofibers (PCNB/HPβCD-IC-NF) with
Highly antibacterial electrospun double-layer mats for preventing secondary wound damage and promoting unidirectional water conduction in wound dressings
The efficient absorption of wound exudate and the prevention of soft tissue infection are major concerns in wound repair. Good
Fast-Disintegrating Nanofibrous Web of Pullulan/Griseofulvin–Cyclodextrin Inclusion Complexes
Griseofulvin (GSF) is one of the most widely used antifungal suffering from low water solubility and limited bioavailability. Here, cyclodextrin
The review article ‘Molecular Mind Games’ describes the latest developments in cyclodextrin research for the treatment of brain disorders
The human brain is a complex and intricate network of cells and molecules that control every aspect of our behaviour
HPBCD in an approved non-replicating adenoviral vector-based gene therapy product
ADSTILADRIN is a non-replicating adenoviral vector-based gene therapy approved by FDA in December 2022 for the treatment of adult patients
Parkinson’s Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment
Parkinson-disease-patient-derived cells presented differences in their energetic profile, imbalanced proliferation, apoptosis, mitophagy, and a reduced differentiation efficiency to tyrosine hydroxylase
An overview of recent patents and future perspective based on cyclodextrin complexation
This article covers information about cyclodextrin and its various derivatives, its different manufacturing process, physicochemical properties, advantages, and recent advancements.
Natamycin/HPBCD eye drops for the treatment of fungal keratitis
Fungal keratitis (FK) is a corneal mycotic infection that can lead to vision loss. Furthermore, the severity of FK is