HPBCD is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease
Niemann-Pick type C1 (NPC1) disease is a fatal neurovisceral disease for which there are no FDA approved treatments, though cyclodextrin
Tag: HPBCD
CD-enhanced soil remediation by ‘sugar flushing’
There are several soil remediation technologies utilizing cyclodextrins as solubilizers of organic contaminants (Gruiz et al. 2019). Soil washing/flushing with
Cyclodextrin in ice cream
In these hot days it might be refreshing even reading on ice creams. Cyclodextrin can improve the texture, stabilize the
National Niemann Pick Disease Family Conference
The annual National Niemann Pick Disease Family Conference will be held on August 15-18, 2019, in Bloomington, US. The conference
Carbohydrate drugs (Part 5) (Oligosaccharides, cyclodextrins)
First let’s talk about one of the biggest achievements in the history of cyclodextrin research: Sugammadex. Sugammadex (SGM) (BridionTM) (1a)
CTD Holdings Announces Plan to Launch Clinical Trial of Trappsol (R) Cyclo (TM) in Alzheimer’s Disease
CTD Holdings, Inc., a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical
Might cyclodextrin uptake mask antimicrobial activity?
Could excipients mask a bioactive effect? The team of López-Nicolás J.M. (University of Murcia, Spain) has recently published a curious
A HPBCD solubilized novel fusion inhibitor of influenza virus was found orally active in mice
A group of researchers employed by different subsidiaries of Janssen Research & Development, Scripps Research Institute, Department of Epidemiology, as well
Novel polyrotaxane for Niemann Pick disease type C treatment
The team of Gerhard Wenz (Saarland University, Germany) has published a novel polyrotaxane: hydroxypropyl-β-cyclodextrin(HPBCD):poly(decamethylenephosphate) which has several advantages over HPBCD
Antidepressant drug to treat sepsis
Sepsis is an often deadly complication of infection in which systemic inflammation damages the vasculature, leading to tissue hypoperfusion and