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Tag: HPBCD

June 11, 2026 Drug delivery / Pharma applications

Chitosan-coated cyclodextrin-based niosomes enable enhanced nose-to-brain delivery of rivastigmine and asiaticoside for Alzheimer’s disease

The co-delivery of rivastigmine hydrogen tartrate (RHT) and asiaticoside (AS) offers a promising strategy for enhancing acetylcholinesterase (AChE) inhibition in

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June 3, 2026 CD as API / CD derivatives / Drug delivery / Pharma applications

Nano-Enabled Toxicity of Pharmaceutical Excipients

Nanotechnology has brought revolutionary advances in the pharmaceutical field. Among drug delivery systems, nanocarriers, which enhance the solubility, stability and

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June 1, 2026 Drug delivery / Pharma applications

Biphasic dissolving microneedles with cyclodextrin inclusion complexes for enhanced delivery of poorly soluble drugs

Dissolving microneedles (DMNs) have been widely investigated for transdermal drug delivery, yet their clinical translation and commercialization remain limited, primarily

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May 26, 2026 Agriculture / CD derivatives

Methyl salicylate/methyl-β-cyclodextrin inclusion complex modulates plant defense against cold and heat stress

Methyl salicylate (MeSA), a known defense modulator, holds promise as a biostimulant; however, its volatility and poor aqueous solubility limit

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May 18, 2026 CD as API / Pharma applications

HPBCD against acute and subacute infarcts in a mouse model of ischemic stroke

HPβCD has also been investigated as an active pharmaceutical ingredient (API) for the prospective treatment of ischemic stroke. We previously

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May 5, 2026 Drug delivery / Pharma applications / Uncategorized

Cyclodextrin complexation of selected tyrosine kinase inhibitors

The comprehensive physicochemical characterization and cyclodextrin complexation of four tyrosine kinase inhibitors — erlotinib, gefitinib, vandetanib, and lapatinib — were

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April 21, 2026 Drug delivery / Pharma applications

CD in prevention of dengue-induced lethality

Annexin A1 (AnxA1) was identified as an endogenous regulator of inflammation in dengue. Treatment with the AnxA1 peptidomimetic, Ac2-26, improved

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April 20, 2026 Drug delivery / Pharma applications

A Bubble-Driven Drug Delivery System Enhances Oral Absorption and Antipyretic Efficacy of Poorly Water-Soluble Andrographolide

The Bubble-Driven Drug Delivery System (BDDS, a new name for effervescent formulations) was optimized through the screening of effervescent formulations

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April 17, 2026 Drug delivery / Pharma applications

Improving Drug Bioavailability with Cyclodextrin Complexes: An integrative meta-modeling approach

This study integrates molecular modeling and meta-analysis to evaluate the pharmacokinetic performance and molecular stability of various cyclodextrin-drug systems. A

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April 6, 2026 CD as API / Pharma applications

HPβCD’s Promise in Treating Ischemic Stroke

Ischemic stroke is a leading cause of mortality and long-term disability worldwide, with limited pharmacological interventions available. 2-hydroxypropyl-β-cyclodextrin (HPβCD), a

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Recent Posts

  • Call for Chapters: Cyclodextrins for Next-Generation Electronics and Energy Storage
  • Call for Chapters: Cyclodextrins in Nutraceuticals 
  • Comparison of the siRNA and mRNA Carrying Capacity of Quaternary Ammonium β-Cyclodextrin Polymer and Polyethylenimine
  • Call for Chapters: Cyclodextrins in Phytomedicine
  • Poly-CD-PEG-camptothecin Combined with Olaparib  in People With Relapsed/​Refractory Small Cell Lung Cancer (Clinical trial)

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Top Posts

  • Call for Chapters: Cyclodextrins in Phytomedicine
  • Call for Chapters: Cyclodextrins in Nutraceuticals 
  • Poly-CD-PEG-camptothecin Combined with Olaparib  in People With Relapsed/​Refractory Small Cell Lung Cancer (Clinical trial)
  • Comparison of the siRNA and mRNA Carrying Capacity of Quaternary Ammonium β-Cyclodextrin Polymer and Polyethylenimine
  • Call for Chapters: Cyclodextrins for Next-Generation Electronics and Energy Storage
  • New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA
  • GRAS status of CD derivatives
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Citric acid cross-linked β-cyclodextrins: A review of preparation and environmental/biomedical application
  • A Cyclodextrin Surprise in a Japanese Supplement

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