Disruption of Lipid Sorting and Endosomal Transport in Cyclodextrin-mediated Cytotoxicity
The effects of native and modified CDs in human renal proximal tubule cells was studied using complementary imaging, flow cytometry,
Tag: methyl BCD
Impact of Cholesterol Depletion by Methyl BCD on Dopamine Transmission Dynamics in Brain
Disrupted brain cholesterol homeostasis is implicated in neurological disorders involving aberrant dopamine (DA) signaling; however, the direct effects of cholesterol
Amitriptyline in reducing bronchoconstriction effects compared to methyl BCD
Bronchial asthma is a chronic inflammatory disease with rising prevalence worldwide. Apart from the immunological role of the tricyclic antidepressant
Methyl BCD-based supramolecular polyrotaxane as theranostic in anticancer immunotherapy
Despite the tremendous therapeutic promise of activating stimulators of interferon genes (STING) enable to prime robust de novo T-cell responses,
Enhanced solubility, stability, and bioavailability of astilbin via inclusion complexes formation with methyl-β-cyclodextrin
This article investigates the complexation of astilbin (Ast), a poorly soluble flavonoid, with methyl-β-cyclodextrin (M-β-CD) to enhance its solubility, stability,
Cyclodextrin attenuates atherosclerosis by diminishing gasdermin D (GSDMD)-mediated pyroptosis
Atherosclerosis is a progressive inflammatory disease characterized by the accumulation of lipids in the arterial vessel wall, which begins in
Does a Gut-Joint Axis exist? (Potential Role of bile acids and microbiome in Osteroarthritis treatment)
The gut-joint axis is a bidirectional communication and interaction between the gastrointestinal tract (gut) and the joints. It involves the
Cyclodextrin-based materials for pulmonary delivery: Insights and challenges
The literature provides a large range of information on the manufacturing of CD-based materials for pulmonary delivery, the characterization of
Rapid test for identification of heptakis (2,6-di-O-methyl) β-cyclodextrin in isomeric mixtures
A rapid test was worked out to identify single isomer heptakis(2,6-di-O-methyl) β-cyclodextrin (2,6-DIMEB), an isomer with distinct methylation pattern compared
Serum-free media
Albumin is a crucial component of serum-free media, playing a significant role in ex vivo cell culture as a lipid carrier