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Tag: methyl BCD

June 9, 2023 Drug delivery

Cyclodextrins and Their Polymers Affect Human Serum Albumin’s Interaction with Drugs Used in the Treatment of Pulmonary Infections

Respiratory infectious diseases have challenged medical communities and researchers. Ceftriaxone, meropenem and levofloxacin are widely used for bacterial infection treatment,

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March 17, 2023 Life sciences

Methyl BCD alters cell envelop studied by AFM

To elucidate the involvement of the cell envelope in the stiffness of sickle cells, methyl-β-cyclodextrin (MβCD), a putative cholesterol-depleting reagent

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February 28, 2023 CD as API / Pharma applications / Uncategorized

Dimethyl-α-cyclodextrin induces capacitation by removing phospholipids from the plasma membrane of mouse sperm

Dimethyl-alpha-CD (DMACD) was found to enhance sperm fertilization ability by removing phospholipids. It was concluded that in addition to the

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February 3, 2023 CD as API / CD derivatives / Pharma applications

Mannose-modified methyl-β-cyclodextrin suppresses tumor growth

Methylated β-cyclodextrin (MeβCD) can extract cholesterol from lipid rafts and induce apoptosis in cancer cells by inhibiting activation of the

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October 20, 2022 CD as API / CD derivatives / Pharma applications

Eye drops containing methyl BCD as active – clinical trial

Cloudbreak Therapeutics, LLC has sponsored a multicenter, randomized, double-masked, vehicle-controlled, parallel group study using CBT-008 (buffered solution of methyl BCD)

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April 29, 2021 CD as API / Drug delivery / Pharma applications

Targeting Lipid Rafts as a Strategy Against Coronavirus

Lipid rafts are functional membrane microdomains containing sphingolipids, including gangliosides, and cholesterol. These regions are characterized by highly ordered and

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February 18, 2021 Agriculture / CD as API / Environmental

The use of β-CDs to improve honey bee health

Honey bees are essential members of the natural ecosystems and the modern agriculture, yet their colonies are collapsing worldwide. In

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October 5, 2020 CD as API / Pharma applications

An antibody–supermolecule conjugate for cancer chemotherapy

In this study, antibody–supermolecule conjugates, consisting of a tumor-specific antibody and acid-labile polyrotaxane containing methylated b-cyclodextrin (Me-PRX), were designed to

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April 14, 2020 Pharma applications / Uncategorized

Modulation of Plasma Membrane Composition and Microdomain Organization by methyl beta-CD in B16-F10 Mouse Melanoma Cells

The most interesting finding of Crui et al. in their recently published paper [1] for the readers of the Cyclodextrin

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March 30, 2020 CD as API / Pharma applications

Role of membrane cholesterol in virus infection: CDs and plant sterols against SARS-COV-2

A recent review of Italian researchers emphasized the role of membrane lipids in the infectivity mechanism of SARS-COV-2 (Covid-19) based

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  • Application of Cyclodextrin for Cancer Immunotherapy
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  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-β-cyclodextrin column using polar organic mode
  • Inclusion complexes of conducting arylidene copolymers as corrosion inhibitors for mild steel
  • How air fresheners work?
  • Curcumin/amphiphilic cyclodextrin nanoassemblies: Theoretical andspectroscopic studies to address their debut in anticancer therapy
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