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Tag: methyl BCD

March 17, 2023 Life sciences

Methyl BCD alters cell envelop studied by AFM

To elucidate the involvement of the cell envelope in the stiffness of sickle cells, methyl-β-cyclodextrin (MβCD), a putative cholesterol-depleting reagent

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February 28, 2023 CD as API / Pharma applications / Uncategorized

Dimethyl-α-cyclodextrin induces capacitation by removing phospholipids from the plasma membrane of mouse sperm

Dimethyl-alpha-CD (DMACD) was found to enhance sperm fertilization ability by removing phospholipids. It was concluded that in addition to the

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February 3, 2023 CD as API / CD derivatives / Pharma applications

Mannose-modified methyl-β-cyclodextrin suppresses tumor growth

Methylated β-cyclodextrin (MeβCD) can extract cholesterol from lipid rafts and induce apoptosis in cancer cells by inhibiting activation of the

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October 20, 2022 CD as API / CD derivatives / Pharma applications

Eye drops containing methyl BCD as active – clinical trial

Cloudbreak Therapeutics, LLC has sponsored a multicenter, randomized, double-masked, vehicle-controlled, parallel group study using CBT-008 (buffered solution of methyl BCD)

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April 29, 2021 CD as API / Drug delivery / Pharma applications

Targeting Lipid Rafts as a Strategy Against Coronavirus

Lipid rafts are functional membrane microdomains containing sphingolipids, including gangliosides, and cholesterol. These regions are characterized by highly ordered and

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February 18, 2021 Agriculture / CD as API / Environmental

The use of β-CDs to improve honey bee health

Honey bees are essential members of the natural ecosystems and the modern agriculture, yet their colonies are collapsing worldwide. In

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October 5, 2020 CD as API / Pharma applications

An antibody–supermolecule conjugate for cancer chemotherapy

In this study, antibody–supermolecule conjugates, consisting of a tumor-specific antibody and acid-labile polyrotaxane containing methylated b-cyclodextrin (Me-PRX), were designed to

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April 14, 2020 Pharma applications / Uncategorized

Modulation of Plasma Membrane Composition and Microdomain Organization by methyl beta-CD in B16-F10 Mouse Melanoma Cells

The most interesting finding of Crui et al. in their recently published paper [1] for the readers of the Cyclodextrin

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March 30, 2020 CD as API / Pharma applications

Role of membrane cholesterol in virus infection: CDs and plant sterols against SARS-COV-2

A recent review of Italian researchers emphasized the role of membrane lipids in the infectivity mechanism of SARS-COV-2 (Covid-19) based

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February 6, 2020 CD as API / Pharma applications

Antiviral effect of C-reactive polymer and methyl beta-cyclodextrin via blocking autophagy through interactions with cell membrane cholesterol

Spanish researchers recently published on the mechanisms involved in antiviral activity of zebrafish C-reactive protein-like protein (CRP1-7) against the spring

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  • Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous Solutions

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