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Tag: Dexolve

May 17, 2022 Drug delivery / Pharma applications

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin

In terms of solubilization effect, it was found that phase solubility of RDV increased significantly from intrinsic 1.7 mmol/L at

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May 13, 2022 Drug delivery / Pharma applications

Buccal administration of remdesivir – still far from reality

As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,

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April 29, 2022 Drug delivery / Pharma applications

FDA Approves First COVID-19 Treatment for Young Children

The press release was published on the U.S. Food and Drug Administration website: On Apr. 26, 2022, the U.S. Food

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April 12, 2022 Drug delivery / Pharma applications

Sulfobutylation of Beta-Cyclodextrin Enhances the Complex Formation with Mitragynine: An NMR and Chiroptical Study

Mitragynine (MTR), the main indole alkaloid of the well-known plant kratom (Mitragyna speciosa) is a partial agonist on the opioid

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April 11, 2022 Drug delivery / Pharma applications

Use of Antivirals in SARS-CoV-2 Infection. Critical Review of the Role of Remdesivir

The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of

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March 26, 2022 Events

CycloLab awarded by 2021 Innovation Grand Prize

The Hungarian Association of Innovation awarded CycloLab with this prestigious prize due to its meaningful and very profitable innovation concerning

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February 17, 2022 Drug delivery / Pharma applications

Effect of Sulfobutylether-β-CD on Silver Nanoparticles Synthesis and Stability in aqueous solution

An innovative application of sulfobutylether-β-CD (SBE-βCD) regarding the preparation of spherical and monodispersed silver nanoparticles (AgNPs) was recently described [1].

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January 25, 2022 Drug delivery / Pharma applications

FDA Approves Veklury® (Remdesivir) for the Treatment of Non-Hospitalized Patients at High Risk for COVID-19 Disease Progression

— Approval Based on Phase 3 Data Showing Veklury Significantly Reduced Risk of Hospitalization By 87% Compared with Placebo —

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January 18, 2022 Drug delivery / Pharma applications

Voriconazole–Cyclodextrin Supramolecular Ternary Complex-Loaded Ocular Films

Prof. Lewis’ group used the multicomponent complex formation of CDs with hydroxy acids to improve the pharmacokinetic of voriconazole. Fungal

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November 25, 2021 Drug delivery / Pharma applications

Remdesivir interactions with sulfobutylether-b-cyclodextrins: A case study using selected substitution patterns

A structural and thermodynamic analysis for the interaction between SBECD and neutral or protonated remdesivir has been performed using multiple

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Recent Posts

  • Cholesterol/β-cyclodextrin complexation revisited by combined experimental and computational approaches
  • Cyclodextrin improve the composition of dairy products, an example in food industry
  • International Conference on Bioinspiration and Biobased​ Materials
  • Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin
  • Have you ever washed your hands with HPBCD-containing soap? Check it out!

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Top Posts

  • Cyclodextrin improve the composition of dairy products, an example in food industry
  • Cholesterol/β-cyclodextrin complexation revisited by combined experimental and computational approaches
  • Have you ever washed your hands with HPBCD-containing soap? Check it out!
  • Program of International Cyclodextrin Symposium
  • Promising results of sulfobutylether-β-cyclodextrin based low-melting mixture in the solubilization of steroids 
  • How air fresheners work?
  • SBECD partly inhibits the renal excretion of anionic drugs
  • International Conference on Bioinspiration and Biobased​ Materials
  • Mallinckrodt gave up further development of adrabetadex (VTS-270; HPBCD)
  • Flexible carbon membrane supercapacitor based on γ-cyclodextrin-MOF

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