Novel delivery systems for Resveratrol
A novel polymer, β-cyclodextrin-epichlorohydrin-cyanoguanidine polymer (CDPC) was synthesized to evaluate its potential as an efficient carrier for the encapsulation of
Tag: Dexolve
Cantrixil’s Career Shift: Orphan Drug Encapsulated in Alpha-Cyclodextrin Changes Hands (and Cyclodextrin)
On 31 March, 2025, Kazia Therapeutics (Australia) Announced sale of intellectual property and trademarks rights for Cantrixil, a product that
Lessons from space studies on stability of a drug / cyclodextrin composition
Assessing the stability of drugs in space is crucial for future missions due to various environmental factors such as radiation,
Dual function of sulfobutylether-betadex in antiviral Veklury®: a remdesivir solubilizer and an effector
A recent publication written by a team of University of Debrecen reported that the excipient, sulfobutylether-betadex (SBECD), in Veklury® (remdesivir
New US patent for SBECD purification by CycloLab
The status of US patent application 17/344,217 (“Purification of sulfobutylated cyclodextrins with specific ion exchange resins” by CycloLab, Hungary) was
Cyclodextrin-based delivery systems in parenteral formulations: A critical update review
Amongst all the strategies that can be useful in the development of parenteral formulations, the formation of water-soluble host-guest inclusion
Nano-formulations containing SBECD
Various nano-formulations containing SBECD have been studied in order to utilize the inclusion complex forming (solubilizing, stabilizing) ability of this
Clinical trial: Allopregnalonone/Dexolve for Post Traumatic Stress Disorder
About 6.4% of the U.S. population suffers from posttraumatic stress disorder (PTSD). Trauma-focused psychotherapies are generally effective in PTSD, but
Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin
In terms of solubilization effect, it was found that phase solubility of RDV increased significantly from intrinsic 1.7 mmol/L at
Buccal administration of remdesivir – still far from reality
As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,