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Tag: Dexolve

January 18, 2023 CD derivatives / Drug delivery / Pharma applications

New US patent for SBECD purification by CycloLab

The status of US patent application 17/344,217 (“Purification of sulfobutylated cyclodextrins with specific ion exchange resins” by CycloLab, Hungary) was

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August 25, 2022 Drug delivery / Pharma applications

Cyclodextrin-based delivery systems in parenteral formulations: A critical update review

Amongst all the strategies that can be useful in the development of parenteral formulations, the formation of water-soluble host-guest inclusion

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August 22, 2022 Drug delivery / Pharma applications

Nano-formulations containing SBECD

Various nano-formulations containing SBECD have been studied in order to utilize the inclusion complex forming (solubilizing, stabilizing) ability of this

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August 19, 2022 Drug delivery / Pharma applications

Clinical trial: Allopregnalonone/Dexolve for Post Traumatic Stress Disorder

About 6.4% of the U.S. population suffers from posttraumatic stress disorder (PTSD). Trauma-focused psychotherapies are generally effective in PTSD, but

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May 17, 2022 Drug delivery / Pharma applications

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin

In terms of solubilization effect, it was found that phase solubility of RDV increased significantly from intrinsic 1.7 mmol/L at

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May 13, 2022 Drug delivery / Pharma applications

Buccal administration of remdesivir – still far from reality

As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,

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April 29, 2022 Drug delivery / Pharma applications

FDA Approves First COVID-19 Treatment for Young Children

The press release was published on the U.S. Food and Drug Administration website: On Apr. 26, 2022, the U.S. Food

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April 12, 2022 Drug delivery / Pharma applications

Sulfobutylation of Beta-Cyclodextrin Enhances the Complex Formation with Mitragynine: An NMR and Chiroptical Study

Mitragynine (MTR), the main indole alkaloid of the well-known plant kratom (Mitragyna speciosa) is a partial agonist on the opioid

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April 11, 2022 Drug delivery / Pharma applications

Use of Antivirals in SARS-CoV-2 Infection. Critical Review of the Role of Remdesivir

The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of

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March 26, 2022 Events

CycloLab awarded by 2021 Innovation Grand Prize

The Hungarian Association of Innovation awarded CycloLab with this prestigious prize due to its meaningful and very profitable innovation concerning

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  • Cyclodextrin related patent application of 2023 Nobel laureate Katalin Karikó
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  • Biomimetic nanoparticles to enhance the reverse cholesterol transport for selectively inhibiting development into foam cell in atherosclerosis
  • Ex Vivo Drug Screening Assay with Artificial Membranes: Characterizing Cholesterol Desorbing Competencies of Beta-Cyclodextrins

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  • Cyclodextrin in Vaccines
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  • Ex Vivo Drug Screening Assay with Artificial Membranes: Characterizing Cholesterol Desorbing Competencies of Beta-Cyclodextrins
  • Australian company pioneering Cavadextrin for regression of atherosclerosis
  • Cyclodextrin related patent application of 2023 Nobel laureate Katalin Karikó
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  • Ashland webinar — the magic rings: how cyclodextrins can enable drug development
  • How air fresheners work?
  • Curcumin/amphiphilic cyclodextrin nanoassemblies: Theoretical andspectroscopic studies to address their debut in anticancer therapy
  • HPBCD in an approved non-replicating adenoviral vector-based gene therapy product

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