Are cyclodextrins safe for intravitreal injections?
Cyclodextrins are excellent excipients for various routes of administration, the ophthalmic delivery is potentially one of the most useful applications
Tag: RAMEB
Nanofibrous Formulation of Cyclodextrin Stabilized Lipases for Efficient Pancreatin Replacement Therapies
The purpose of enzyme therapies (ERT) is simple: patients who suffer from enzyme deficiency should be treated by administering enzymes
Improvement of Butamben Anesthetic Efficacy by the Development of Deformable Liposomes Bearing the Drug as Cyclodextrin Complex
This work was aimed at enhancing butamben (BTB) anesthetic efficacy by the “drug-in cyclodextrin (CD)-in deformable liposomes” strategy. In the
Molecular lipophilic potential of cyclodextrins
A recent review of Jicsinszky et al. (2021) gave an overview on cyclodextrins’ benefits and limitations in various antiviral drug
Antibiotic-in-cyclodextrin-in-liposomes: formulation development and interactions with model bacterial membranes
Gram-negative bacteria possess numerous defenses against antibiotics, due to the intrinsic permeability barrier of their outer membrane, explaining the recalcitrance
Soil bioremediation by cyclodextrins. A review
Remediation of soils contaminated by organic pollutants has become an urgent necessity worldwide. A wide variety of techniques have been
Cyclodextrin-impregnated masks to prevent the transmission of coronavirus
CycloLab’s submission to InnoCentive Challenge 9934291 – New Technologies to Prevent the Transmission of Coronavirus led to a favorable evaluation.
Use of cyclodextrins as agrochemical delivery system
ADAMA MAKHTESHIM LTD. (Israel) filed a PCT patent application (WO2020084572) that was recently published. The invention relates to preparation and use
In vivo preclinical evaluation of the new 68Ga-labeled beta-cyclodextrin in prostaglandin E2 (PGE2) positive tumor model using positron emission tomography
The cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) pathway plays an important role in tumor development and formation of metastases. It was earlier
Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
The so-called “intrinsic” solubility of cyclodextrins (CDs) and their derivatives is always one of the first and important questions from