Cyclodextrin complexation of selected tyrosine kinase inhibitors
The comprehensive physicochemical characterization and cyclodextrin complexation of four tyrosine kinase inhibitors — erlotinib, gefitinib, vandetanib, and lapatinib — were
Tag: RAMEB
Toxic effects and cellular uptake of functional polyrotaxanes. The little we have learned and the many unknowns still waiting to be discovered.
Cyclodextrins are commonly used as excipients in modern drug delivery, but they also have a less common role as active
Impact of Randomly Methylated Cyclodextrins on Candida albicans
The challenges related to biofilm-associated infections and diseases have prompted scientists to develop strategies aimed at reducing biofilm-forming capacity. Cells
Toxic effects and cellular uptake of functional polyrotaxanes.
The little we have learned and the many unknowns still waiting to be discovered. Cyclodextrins are commonly used as excipients
CDs for fighting against Candida albicans biofilms
The formation of biofilms is one of the most important virulence factors of the opportunistic pathogen Candida albicans. This polymorphic
Development of a nasal spray based on cyclodextrin/hydrophobically-modified hydroxypropyl-methyl cellulose for the prevention of viral respiratory infections
The work aims to develop mucoadhesive and thermo-responsive in situ gelling systems, using hydrophobically-modified hydroxypropyl-methyl cellulose (Sangelose, SG) and beta-cyclodextrin
Statins in Aqueous Cyclodextrin Ocular Preparations
Topical statin therapy holds promise for ocular diseases, such as age-related macular degeneration, but the effective delivery to the posterior
Cholesterol Depletion by Cyclodextrins Reduces Pain Sensation
The nociceptive Transient Receptor Potential Vanilloid 1 (TRPV1) and Ankyrin 1 (TRPA1) channels are predominantly expressed on peptidergic sensory nerves,
Theoretical Calculation of the Solubility and Other Parameters for Poorly Water-Soluble Compounds from Binding Constants of Inclusion Complexes
Experimental determination of solubility is a time-consuming procedure with relatively high reagent consumption. The solubility of poorly water-soluble compounds in
Possible treatment of brain tuberculosis by methyl-β-cyclodextrin–assisted trans-nasal delivery of anti-tuberculosis drugs
Tuberculosis (TB) is prevalent worldwide. One of the most life-threatening manifestation of extrapulmonary tuberculosis is the involvement of central nervous