The revival of cyclodextrins as active pharmaceutical ingredients
Discovered in 1891, cyclodextrins, derived from starchy food, have found many applications in the cosmetic, agriculture, food and pharmaceutical industries
Tag: Alzheimer disease
Treatment of acute and long Covid, diabetes, miocardial infarction, and Alzheimer disease. The potential role of a novel compound, the trasdermal glutathione nano CD complex
Oxidative stress (OS) occurs from excessive reactive oxygen species or a deficiency of antioxidants—primarily endogenous glutathione (GSH). There are many
Gamma-CD polymer a mild cholesterol modulator for Alzheimer disease
The patent application of Renatus (US2024238327 (A1) ― 2024-07-18) claims for a pharmaceutical composition including a gamma-cyclodextrin-based polymer, for prevention and
CDs in therapy of Alzheimer Disease. Recent studies
Alzheimer’s disease (AD) is one of the most prevalent dementia, characterized by irreversible and progressive cognitive dysfunction. Senile plaques, also
Nanoparticles with Green Tea for Inhibition of β-Amyloid Fibrillation
Inhibition of amyloid β protein fragment (Aβ) aggregation is considered to be one of the most effective strategies for the
Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer’s Disease
Plant-derived multitarget compounds may represent a promising therapeutic strategy for multifactorial diseases, such as Alzheimer’s disease (AD). Artemisinin and its
The Single Toxin Origin of Alzheimer’s Disease and Other Neurodegenerative Disorders Enables Targeted Approach to Treatment and Prevention
New data suggest that the aggregation of misfolded native proteins initiates and drives the pathogenic cascade that leads to Alzheimer’s
Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans
The elevated occurrence of debilitating neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), Alzheimer’s disease (AD), Parkinson’s
Merger of Cyclo Therapeutics and Applied Molecular Transport
Cyclo Therapeutics, (Cyclo) a clinical stage company focused on developing therapies for rare and neurological diseases with limited treatment options,
Molecular Mind Games: The Medicinal Action of Cyclodextrins in Neurodegenerative Diseases
This work presents the most recent advances in the research and clinical use of HPβCD against Niemann–Pick disease, a congenital