Book chapter: Functionalized cyclodextrins in drug delivery

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The book : Engineered Biomaterials for Drug Delivery (Edited by: Amit Kumar Nayak, Md Saquib Hasnain and Tejraj M. Aminabhavi)

Woodhead Publishing

Language: English

ISBN: 978-0-323-95751-9

DOI: 10.1016/C2021-0-02764-4

It covers a core selection of engineering approaches and methods to optimize materials for drug delivery, including grafting, cross-linking, thiolation, conjugation, and the functionalization of biomaterials. A wide range of engineered biomaterial types are described, from biopolymers and nanobiomaterials, to metals, ceramics, and composites. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications.

This book chapter on cyclodextrins focuses on selective delivery of anticancer drugs with the use of nanoparticle like cyclodextrin (α, β, γ) functionalized with different agents like mesoporous hydrogels, zeolites, polyethylene glycol (PEG) and many more, to get an improved delivery agent with more efficient transfer for the drugs and increased cytotoxicity for better action on the cancer cells.

Yash Jain, Rudra Upasani, Yash Satam, Aryaman Khatua, Jaya Lakkakula,
19 – Functionalized cyclodextrins in drug delivery, Editor(s): Amit Kumar Nayak, Md Saquib Hasnain, Tejraj M. Aminabhavi, In: Woodhead Publishing Series in Biomaterials, Engineered Biomaterials for Drug Delivery, Woodhead Publishing, 2026, Pages 549-573, ISBN 9780323957519,
https://doi.org/10.1016/B978-0-323-95751-9.00016-7.

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