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Tag: cytotoxicity

July 15, 2026 Pharma applications / Supramolecular systems

Supramolecular guest-host composites of adamantane-modified gelatin and β-cyclodextrin polymers, displaying unexpected rheological and bioinert behavior.

Because of their strong complexation behavior, guest-host interactions between adamantane (Ad) and β-cyclodextrin (CD) are often used to create physically

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July 7, 2026 CD derivatives / Drug delivery / Pharma applications

Poly-β-Cyclodextrin as a Superior Host for Gemcitabine

Gemcitabine remains a vital chemotherapeutic agent, yet its rapid deamination and short systemic persistence necessitate improved delivery strategies. This study

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June 26, 2026 CD derivatives / Gene delivery / Pharma applications

Comparison of the siRNA and mRNA Carrying Capacity of Quaternary Ammonium β-Cyclodextrin Polymer and Polyethylenimine

The study investigates the effectiveness of a cationic cyclodextrin polymer-based delivery system for intracellular transport of RNA molecules. Efficient delivery

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March 20, 2025 Drug delivery / Pharma applications

Biopolymer Composite Materials as Drug Delivery Platforms for Regenerative Pharmacology

Frontiers in Pharmacology calls for papers in thematic issue: Biopolymer Composite Materials as Drug Delivery Platforms for Regenerative Pharmacology. Biopolymer

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February 3, 2025 CD derivatives / Drug delivery / Life sciences / Pharma applications

Cyclodextrins unlock the full potential of lipopeptides — reducing cytotoxicity while keeping their antimicrobial efficacy intact

Over the past decade, the growing threat of antibiotic resistance has intensified interest in antimicrobial peptides and lipopeptides as promising

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May 26, 2023 Drug delivery / Pharma applications

Ensembles of carboxymethyl cyclodextrins on cationic liposomes as highly efficient nanocontainers for the delivery of hydrophobic compounds

The increase of payload is one of the key tasks in creation of nanocontainers for the delivery of bioactive substances

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June 2, 2022 CD derivatives / Gene delivery / Pharma applications

Tetraethylenepentamine-Coated β Cyclodextrin Nanoparticles for Dual DNA and siRNA Delivery

Tetraethylenepentamine-coated β-cyclodextrin (TEPA-BCD) nanoparticles were synthesized, characterized, and evaluated for targeted cell delivery of plasmid DNA and siRNA. The cationic

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May 12, 2022 CD as API / Pharma applications

Cothreading of Unmodified and Monoazidated β-Mixed cyclodextrins in polyrotaxanes for Niemann Pick disease

To establish a method for the orthogonal chemical functionalization of β-cyclodextrin (β-CD)-based polyrotaxane (PRX), unmodified and monoazidated β-CDs (N3-β-CDs) were

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Recent Posts

  • Special Issue titled “Cyclodextrins: Properties and Applications, 4th Edition”
  • Cyclodextrins hit the golf course seven years ago — and they are still there
  • Enhancing Curcumin Efficacy Against Triple-Negative Breast Cancer
  • REVTORPYK™: A New FDA Approval for Gedatolisib/HPBCD composition
  • Reducing Cholesterol with β-CDP: Insights for NPC and AD

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Top Posts

  • Special Issue titled "Cyclodextrins: Properties and Applications, 4th Edition"
  • Cyclodextrins hit the golf course seven years ago — and they are still there
  • REVTORPYK™: A New FDA Approval for Gedatolisib/HPBCD composition
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Enhancing Curcumin Efficacy Against Triple-Negative Breast Cancer
  • Lanosterol eye drops for cataract treatment
  • 22nd International Cyclodextrin Symposium (ICS-22) in India
  • Cyclodextrins against skin aging
  • Amgen Submits Supplemental New Drug Application For KYPROLIS® (carfilzomib)

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