Complexes of lycorine and its hydrochloride
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (Clivia miniata), surprise
Tag: Covid-19
Veklury® (remdesivir) formulations inhibit initial membrane-coupled events of SARS-CoV-2 infection due to their sulfobutylether-β-cyclodextrin content
Background and purpose: Despite its contradictory clinical performance, Veklury® (remdesivir) has a pivotal role in COVID-19 therapy. Possible contributions of the
The Role of Cyclodextrins in COVID-19 Therapy-A Literature Review
Coronavirus disease-19 (COVID-19) emerged in December 2019 and quickly spread, giving rise to a pandemic crisis. Therefore, it triggered tireless
Dietary supplements for the management of COVID-19 symptoms
The aim of this paper is to review the relationship between COVID-19 and nutrition and to discuss to most up-to-date
Case Report: Severe SARS-CoV-2 Infection Treated with Remdesivir in a Patient with ESRD
Remdesivir has emerged as a promising antiviral drug against SARS-CoV-2. However, data regarding the clinical benefits of remdesivir in patients
Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin: stabilization of supersaturated solution by changing pH from 1.7 to 3.5
In terms of solubilization effect, it was found that phase solubility of RDV increased significantly from intrinsic 1.7 mmol/L at
Impact of Remdesivir on SARS-CoV-2 Clearance in a Real-Life Setting: A Matched-Cohort Study
There were 648 patients enrolled in the study (216 cases and 432 controls). Viral clearance (VC) was observed in 490
CIDALTEX® ANTIVIRAL MASKS DURING THE COVID-19 PANDEMIC
Prof. bernard Martel (University of Lille, France) showed how the new cyclodextrin-based mask was developed from the in-lab optimization to
Buccal administration of remdesivir – still far from reality
As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,
Remdesivir administration for Japanese COVID-19 patients undergoing maintenance hemodialysis: a retrospective observation with six case reports
The mortality rate of novel coronaviral disease (COVID-19) patients undergoing dialysis is considerably higher than that of patients with normal