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Tag: Cancer therapy

December 11, 2020 Drug delivery / Pharma applications

Top-line final data from CD-enabled Cantrixil Phase I study confirms prior positive efficacy and safety signals

Kazia Therapeutics Limited, an Australian oncology-focused biotechnology company shared top-line final data from its phase I study of Cantrixil (TRX-E-002-1)

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October 20, 2020 Drug delivery / Pharma applications

Results of HPBCD-enabled MTX110 Phase I Study

Midatech Pharma PLC, an R&D biotechnology company focused on improving the bio‐delivery and biodistribution of medicines, announced encouraging headline results

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October 5, 2020 CD as API / Pharma applications

An antibody–supermolecule conjugate for cancer chemotherapy

In this study, antibody–supermolecule conjugates, consisting of a tumor-specific antibody and acid-labile polyrotaxane containing methylated b-cyclodextrin (Me-PRX), were designed to

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September 15, 2020 CD as API / Pharma applications

Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds: a patent evaluation of US2019343869(A1)

Introduction: Antimicrobial resistance is one of the major scourges for healthcare worldwide, therefore novel investigational approaches are needed to potentiate and

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August 24, 2020 Pharma applications

FDA Approves New KYPROLIS® (SBECD-enabled carfilzomib) Combination Regimen With DARZALEX® (daratumumab) And Dexamethasone

Approval Based on the CANDOR and EQUULEUS Studies in Patients With Relapsed/Refractory Multiple Myeloma Amgen today announced the U.S. Food and

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August 17, 2020 Drug delivery / Pharma applications

Biodegradable β ‐Cyclodextrin Conjugated Gelatin Methacryloyl Microneedle for Delivery of Water‐Insoluble Drug

Transdermal drug delivery offers advantages over nonparenteral routes such as bypassing first-pass metabolism and facile administration. Mammalian skin, however, functions

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August 10, 2020 Drug delivery / Pharma applications

Cyclodextrin as a magic switch in covalent and non-covalent anticancer drug release systems

This article reviews the controlled release of current anticancer drugs based on cyclodextrins as a “flexible switch”, and discusses the

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October 8, 2019 Drug delivery / Pharma applications

Supreme delivery effect of β-cyclodextrin for hypoxic cancer cells recognized in 2019 Nobel prize laureate’s lab

2019 Nobel prize in Physiology or Medicine will be awarded to William G. Kaelin Jr., Sir Peter J. Ratcliffe and

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July 24, 2019 CD derivatives / Drug delivery / Pharma applications

Folate-Decorated Amphiphilic Cyclodextrins as Cell-Targeted Nanophototherapeutics

The group of Prof. Mazzaglia published on a  ternary nanoassembly (SAP) composed of nonionic amphiphilic β-cyclodextrins (amphiphilic CD) incorporating pheophorbide

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July 19, 2019 Drug delivery

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics (edited by Prashant Kesharwani, Kishore Paknikar and Virendra Gajbhiye) and published by

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  • CD-based Nanoparticles from CNR-ISMN Institute of Nanostructured Materials
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