Novel fluorescent CD as theranostic platform for anticancer agents delivery
A novel β-cyclodextrin-aza[5]helicene conjugate as theranostic platform for anticancer agents delivery in cancer cells is reported. The carrier was synthesized
Tag: Cancer therapy
β-Cyclodextrin Encapsulated Platinum(II)-Based Nanoparticles: Photodynamic Therapy and Inhibition of the NF-κB Signaling Pathway in Glioblastoma
This study explores cell death through photodynamic therapy (PDT) with β-cyclodextrin-encapsulated platinum(II)-based nanoparticles (Pt-NPs) and the effect on the NF-κB
Supramolecular polyrotaxane-based nano-theranostics enable cancer-cell stiffening for enhanced T-cell-mediated anticancer immunotherapy
Redox-responsive Methyl-β-cyclodextrin (MeβCD)-based supramolecular polyrotaxanes (MSPs) were fabricated: the amphiphilic diselenide-bridged axle polymer was loaded by MeβCD via the host-guest
Cyclodextrins: Enhancing Drug Delivery, Solubility and Bioavailability for Modern Therapeutics
This review with 238 references explores the multifaceted roles of cyclodextrins in pharmaceutical formulations, ranging from oral, ophthalmic, parenteral, and
Cantrixil’s Career Shift: Orphan Drug Encapsulated in Alpha-Cyclodextrin Changes Hands (and Cyclodextrin)
On 31 March, 2025, Kazia Therapeutics (Australia) Announced sale of intellectual property and trademarks rights for Cantrixil, a product that
Aspirin in cancer therapy
Aspirin, a non-steroidal anti-inflammatory drug (NSAID), has garnered significant attention for its anti-cancer potential. This review [1] explores the pharmacological
New Book Chapter Explores Metallocyclodextrins in Cancer Chemotherapy
A new book chapter titled “Metallocyclodextrins for Cancer Chemotherapy” by Susana Santos Braga is published in the ACS Symposium series
Complexation by γ-cyclodextrin as a way of improving anticancer potential of sumanene
Biological applications of sumanene buckybowl molecule have been widely discussed over the years yet remain still unexplored experimentally. On the other hand,
Cholesterol metabolism in pancreatic cancer and associated therapeutic strategies: cholesterol-lowering agents (CDs and statins)
Pancreatic cancer (PC) remains one of the most lethal cancers due to late diagnosis and high chemoresistance. Despite recent progression
Cyclodextrin-based formulation boosts in vitro anti-tumor potential and lowers toxicity in zebrafish
Paclitaxel (PCTX) is one of the most prevalently used chemotherapeutic agents. However, its use is currently beset with a host