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Tag: Captisol

August 25, 2022 Drug delivery / Pharma applications

Cyclodextrin-based delivery systems in parenteral formulations: A critical update review

Amongst all the strategies that can be useful in the development of parenteral formulations, the formation of water-soluble host-guest inclusion

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August 22, 2022 Drug delivery / Pharma applications

Nano-formulations containing SBECD

Various nano-formulations containing SBECD have been studied in order to utilize the inclusion complex forming (solubilizing, stabilizing) ability of this

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May 17, 2022 Drug delivery / Pharma applications

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin

In terms of solubilization effect, it was found that phase solubility of RDV increased significantly from intrinsic 1.7 mmol/L at

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April 29, 2022 Drug delivery / Pharma applications

FDA Approves First COVID-19 Treatment for Young Children

The press release was published on the U.S. Food and Drug Administration website: On Apr. 26, 2022, the U.S. Food

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April 13, 2022 Drug delivery / Pharma applications

Three Birds, One Excipient: Development of an Improved pH, Isotonic, and Buffered Ketamine Formulation for Subcutaneous Injection

Subcutaneous (SC) ketamine has been found to be effective in pain management, though reports of injection site irritation and sterile

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April 11, 2022 Drug delivery / Pharma applications

Use of Antivirals in SARS-CoV-2 Infection. Critical Review of the Role of Remdesivir

The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of

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January 25, 2022 Drug delivery / Pharma applications

FDA Approves Veklury® (Remdesivir) for the Treatment of Non-Hospitalized Patients at High Risk for COVID-19 Disease Progression

— Approval Based on Phase 3 Data Showing Veklury Significantly Reduced Risk of Hospitalization By 87% Compared with Placebo —

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January 18, 2022 Drug delivery / Pharma applications

Voriconazole–Cyclodextrin Supramolecular Ternary Complex-Loaded Ocular Films

Prof. Lewis’ group used the multicomponent complex formation of CDs with hydroxy acids to improve the pharmacokinetic of voriconazole. Fungal

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November 25, 2021 Drug delivery / Pharma applications

Remdesivir interactions with sulfobutylether-b-cyclodextrins: A case study using selected substitution patterns

A structural and thermodynamic analysis for the interaction between SBECD and neutral or protonated remdesivir has been performed using multiple

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September 21, 2021 Drug delivery / Pharma applications

Marinus Announces FDA Acceptance for Filing and Priority Review of NDA for SBECD-enabled Ganaxolone in CDKL5 Deficiency Disorder

Marinus Pharmaceuticals, Inc. , a pharmaceutical company dedicated to the development of innovative therapeutics to treat seizure disorders, announced that

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Recent Posts

  • Bacteroides uniformis and its preferred substrate, α-cyclodextrin, enhance endurance exercise performance in mice and human males
  • Waterproof and durable luminescent textiles with HPBCD for marine rescue
  • Small anticancer drug release by light
  • Patent application on reduction of envelope viral particle number in a composition containing cyclodextrin
  • γ-Cyclodextrin/Epigallocatechin-3-gallate Inclusion Complexes as Efficient Antioxidants for Preservation of Shrimp Surimi Products

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Top Posts

  • Bacteroides uniformis and its preferred substrate, α-cyclodextrin, enhance endurance exercise performance in mice and human males
  • Lanosterol eye drops for cataract treatment
  • Waterproof and durable luminescent textiles with HPBCD for marine rescue
  • New book: Cyclodextrins - new Perspectives
  • Small anticancer drug release by light
  • γ-Cyclodextrin/Epigallocatechin-3-gallate Inclusion Complexes as Efficient Antioxidants for Preservation of Shrimp Surimi Products
  • Cyclodextrin Metal-Organic Framework as a Broad-Spectrum Potential Delivery Vehicle for the Gasotransmitters
  • Published compilation of the list of approved cyclodextrin-containing drug products
  • Pilocarpine eye drops (Vuity)
  • MIT scientists filed patent for HPBCD treatment in Alzheimer's disease

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