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Tag: Captisol

November 12, 2019 Drug delivery / Pharma applications

Ligand Presents Positive Results from Phase 1 Clinical Trial of Captisol-enabled Iohexol

Ligand Pharmaceuticals Incorporated presented positive results from a Phase 1 clinical trial of its Captisol-enabled (CE) Iohexol program at ASN

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October 3, 2019 Pharma applications

Positive Results With SBECD-enabled Ganaxolone in Phase 2 Refractory Status Epilepticus Trial

Marinus Pharmaceuticals, a pharmaceutical company dedicated to the development of innovative therapeutics to treat epilepsy, depression and other neuropsychiatric disorders,

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September 26, 2019 Pharma applications / Uncategorized

Amgen’s Kyprolis, J&J’s Darzalex team up on myeloma survival win

After years of slow growth, Amgen’s Kyprolis finally looks poised to break the blockbuster barrier in 2019, and new data

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July 17, 2019 Pharma applications

Ligand Announces Positive Top Line Results from Phase 1 Clinical Trial of Captisol-enabled Iohexol

Ligand Pharmaceuticals Incorporated announced positive top line results from a Phase 1 clinical trial of its internal Captisol-enabled (CE) Iohexol

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June 26, 2019 CD as API / CD derivatives / Pharma applications

Clinical trial on Noninfectious Anterior Uveitis – SBECD offering disease resolution

Aldeyra Therapeutics Announced Results from the SOLACE Trial in Noninfectious Anterior Uveitis. The main points are: Statistical Significance Not Achieved

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May 3, 2019 Pharma applications

Enrollment completed of Phase 1 Clinical Trial of Captisol-enabled Iohexol

Ligand Pharmaceuticals Incorporated announced completion of enrollment of the Company’s Phase 1 clinical trial of its internal Captisol-enabled (CE) Iohexol

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March 25, 2019 Pharma applications

Phase I clinical trial posted on Relative Bioavailability of CE-Iohexol (Captisol-enabled™ Iohexol) Injection

This study is designed to compare the bioavailability of the test Product (CE-Iohexol Injection) and the reference product Iohexol Injection

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March 21, 2019 Drug delivery / Pharma applications

Sage Therapeutics Announces FDA Approval of ZULRESSO™ (SBECD-enabled brexanolone) Injection, the First and Only Treatment Specifically Indicated for Postpartum Depression

Approval based on results from three pivotal trials showing treatment with ZULRESSO provided significant and rapid reduction of depressive symptoms

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January 16, 2019 CD derivatives / Drug delivery / Pharma applications

The monograph of SBECD is official in the European Pharmacopeia

As of January 1st, 2019, besides the long valid (August 1st, 2012) monograph in USP NF for Betadex Sulfobutyl Ether

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January 15, 2019 Drug delivery

Antibiotics degradation products against Alzheimer’s disease

A recent paper in Cell Reports published an interesting finding: polymeric degradation products (compound X and Z, respectively) of antibiotics

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