Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?
In this review, based on 250 references, the general chemical principles of direct cyclodextrin–protein interactions are summarized and highlighted, through
Category: CD as API
Nature.com: HPBCD treatment improves learning and executive function in Alzheimer model mice
Earlier we have reported on a patent appication related to HPBCD treatment in Alzheimer’s disease based on the invention of
Beer to prevent Alzheimer Disease
Beer is one of the oldest and most popular beverages in the world. Its bitter taste comes from the hops
Australian company pioneering Cavadextrin for regression of atherosclerosis
Newsmaker, the Australian Press Release Distribution Service has published the news on “An Australian pioneering a medical breakthrough treatment that
Eye drops containing methyl BCD as active – clinical trial
Cloudbreak Therapeutics, LLC has sponsored a multicenter, randomized, double-masked, vehicle-controlled, parallel group study using CBT-008 (buffered solution of methyl BCD)
Inclusion Solves Insolubility ―Translational Research Cycle from Bedside to Bench and Bench to Bedside for Drug Development Targeting Niemann-Pick Disease Type C
Cyclodextrins (CDs) are used not only as pharmaceutical excipients but also as active pharmaceutical ingredients. CDs can act as artificial
Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis
A promising therapy for atherosclerosis treatment was designed by targeting LXR receptor (LXR) on atherosclerotic macrophage, where LXR activation could
Monosubstituted Maltosyl Cyclodextrins for the Potential Treatment of NPC
Niemann-Pick type C is a sever lysosomal storage disease, commonly refereed as ‘children’s Alzheimer’. There is no cure for it
MIT scientists filed patent for HPBCD treatment in Alzheimer’s disease
Li-Huei Tsai, director of Picower Institute for Learning and Memory (Massachusetts Institute of Technology) and her coworkers recently filed a patent
Application of cyclodextrins for detoxification purposes and/or as antidotes: Still more questions than answers
Microencapsulation of drugs with cyclodextrins (CDs) is a commonly applied strategy to solubilize lipophilic drugs in aqueous environment and/or to