Cyclo Therapeutics Inc. Commences Commercial-Scale Manufacturing for Trappsol® Cyclo™
On July 27, the Cyclo Therapeutics, a clinical stage biotechnology firm dedicated to developing life-changing medicines through science and innovation
Category: CD as API
Possible immunoglobulin-E-dependent sugammadex-induced anaphylaxis caused by an epitope other than γ-cyclodextrin: a case report
A 55-year-old Japanese man underwent a laryngectomy under general anesthesia. One month before laryngectomy, he had undergone laryngoscopy under general
Alpha-CD to prevent retinopathy progression
Previous work highlights the detrimental effect elevated retinal cholesterol levels have on diabetic retinopathy (DR) progression. We have shown that
Recent reviews on cyclodextrins against SARS-CoV-2
Recent reviews emphasized the role of membrane lipids in the infectivity mechanism of SARS-COV-2. Cholesterol-rich parts of cell membranes serve
Mallinckrodt gave up further development of adrabetadex (VTS-270; HPBCD)
Mallinckrodt Pharmaceuticals has reached an agreement to divest and transfer the Investigational New Drug (IND) application for experimental drug adrabetadex
Antibacterial and Cytotoxic Effects of Cyclodextrin-Triazole-Titanium Based Nanocomposite
The antibacterial activity of triazole functionalized cyclodextrin (CD.Click) and cyclodextrin-triazole-titanium based nanocomposite (CD.COM) was evaluated. The results indicated that CD.Click
Molecular lipophilic potential of cyclodextrins
A recent review of Jicsinszky et al. (2021) gave an overview on cyclodextrins’ benefits and limitations in various antiviral drug
Cyclodextrins in the antiviral therapy
This review discusses the basic properties of the different cyclodextrin derivatives, their potential in antiviral formulations, and the prevention and
Weakly acidic carboxy group-grafted β-cyclodextrin-threaded acid-degradable polyrotaxanes for modulating protein interaction and cellular internalization
To improve the therapeutic potential of β-cyclodextrin (β-CD)-threaded acid-degradable polyrotaxanes (β-CD PRXs) in cholesterol-related metabolic disorders, the effect of carboxylation
Nitric oxide and COVID-19
A clinical trial in United Kingdom confirms SaNOtize’s breakthrough treatment for COVID-19 SaNOtize R. & D. Corp, a Canadian Biotech