Digital Event on Orphan Drugs and Rare Diseases
The “2nd Edition Digital Event on Orphan Drugs and Rare Diseases (GMT)”, a virtual meeting place for the rare disease
Category: CD as API
Alpha-CD-containing oral spray to inhibit the SARS-CoV-2 endocytosis
Italian researchers developed an oral spray (Endovir Stop) containing alpha-cyclodextrin (0.2%) and hydroxytyrosol (3.8%) for the improvement of the defenses
Oxidized CD bisulfite against influenza A virus
Previous reports have demonstrated that compounds based on sulfo derivatives of oligo- and polysaccharides possess high antiviral activity. In this
Cholesterol chelator, HPβCD for renal diseases
There is increasing evidence that accumulation of intracellular lipids in the kidney contributes to the pathogenesis and progression of kidney
Treatment of Niemann-Pick Disease Type C using crosslinked 2-hydroxypropyl-β-cyclodextrin
Niemann-Pick Disease Type C (NPC) is a severe neurovisceral disorder that is pathophysiologically characterized by intracellular transport abnormalities leading to
Hydroxypropyl-β-cyclodextrin causes massive damage to the developing auditory and vestibular system
2-hydroxypropyl-β-cyclodextrin (HPβCD), a cholesterol chelator used to treat Niemann-Pick C1 (NPC1) lysosomal storage disease, causes hearing loss in mammals by
New cyclodextrin with orphan drug designation: SBECD
ReVision Therapeutics, Inc., a privately-held, early stage biopharmaceutical company focused on the development and commercialization of innovative therapies for ocular
Cyclo Therapeutics Phase 3 Pivotal Program Can Begin Enrollment Per US FDA
Cyclo Therapeutics will now proceed in the US with its Phase 3 clinical trial of Trappsol® Cyclo™ for treatment of Niemann-Pick
An antibody–supermolecule conjugate for cancer chemotherapy
In this study, antibody–supermolecule conjugates, consisting of a tumor-specific antibody and acid-labile polyrotaxane containing methylated b-cyclodextrin (Me-PRX), were designed to
Use of cyclodextrin or its complexes as a potential treatment against the 2019 novel coronavirus
Coronavirus 2 is a member of a virus family with lipid envelope that fuses with host cell through endocytosis, internalizing