Sugammadex analog water soluble BCD polymer for peptide complexes
In this work, an integrated biophysical and biological study is presented describing both the structural and biological features of the
Category: CD as API
Sugammadex vs Neostigmine: Effects on Obese Patients’ Recovery
Compared with neostigmine, sugammadex promotes faster neuromuscular recovery, but its impact on diaphragmatic function and respiratory recovery in the morbidly
Sugammadex vs Neostigmine for Reversal of Neuromuscular Blockade and Association with Postoperative Atelectasis After Video-Assisted Thoracoscopic Surgery: A Propensity Score-Matched Cohort Study
Atelectasis means a collapse of the whole lung or an area of the lung. It’s one of the most common breathing
HPβCD’s Promise in Treating Ischemic Stroke
Ischemic stroke is a leading cause of mortality and long-term disability worldwide, with limited pharmacological interventions available. 2-hydroxypropyl-β-cyclodextrin (HPβCD), a
Phosphorylated Beta-cyclodextrin as a New Bone-Targeting Drug Delivery System Could Change the Treatment of Osteoporosis and Other Bone Diseases
Researchers in Japan have developed a promising new drug delivery platform that not only carries medicines directly to bone, but
Recent papers on Cyclodextrins in Nature
In Scientific Reports, a Japanese team investigated these effects for α-CD derivatives with various replaced substituents from the perspective of
Evaluation of the Potential Therapeutic Effects of HPβCD and SBEβCD in a Mouse Model of Acute Ulcerative Colitis
A Nanjing, China based research group designed a tailored investigation [1] based on a surprising previous study [2]. In they
HPBCD accesses acute and subacute infarcts in a mouse model of ischemic stroke
Ischemic stroke is a leading cause of mortality and long-term disability worldwide, with limited pharmacological interventions available. Researchers in Arizona
HPαCD Therapy: A Breakthrough for Krabbe Disease Treatment
Several North-American Universities worked together to find hydroxzpropyl-alpha-cyclodextrin(HPaCD) for the treatment of Krabbe disease. The deficiency of β-galactosylceramidase causes a
Toxic effects and cellular uptake of functional polyrotaxanes. The little we have learned and the many unknowns still waiting to be discovered.
Cyclodextrins are commonly used as excipients in modern drug delivery, but they also have a less common role as active