The science reported that the drug plitidepsin (aplidin), which has limited clinical approval, possesses antiviral activity (IC90 = 0.88 nM) 27.5-fold
There is increasing evidence that accumulation of intracellular lipids in the kidney contributes to the pathogenesis and progression of kidney
Niemann-Pick Disease Type C (NPC) is a severe neurovisceral disorder that is pathophysiologically characterized by intracellular transport abnormalities leading to
Scientific reports (Nature) has published 10 cyclodextrin-related papers in the last 3 months. Here is a selection: Parvez, S., Yadagiri,
Coronavirus 2 is a member of a virus family with lipid envelope that fuses with host cell through endocytosis, internalizing
The plasma membrane microdomain lipid rafts have been found by researchers to be involved in the replication cycle of numerous
CycloLab’s submission to InnoCentive Challenge 9934291 – New Technologies to Prevent the Transmission of Coronavirus led to a favorable evaluation.
Strategic drug repurposing in combination with rapid testing of established molecular targets could provide a pause in disease progression and
Making a comparison between CDs and the unique Ring of the legendary novel of The Lord of the Rings, J.
There are two possible mechanisms behind the ototoxicity of 2-hydroxypropyl-β-cyclodextrin (HPBCD) treatment. One is : the possible interaction of HPBCD