Update: FDA approves HPBCD-enabled tecovirimat against pox virus
As reported earlier Siga Technologies filed a patent application in the USA describing cyclodextrin solubilized tecovirimat (ST-246). Tecovirimat has low
A forum for researchers, students and applicants in the field of cyclodextrin technology
As reported earlier Siga Technologies filed a patent application in the USA describing cyclodextrin solubilized tecovirimat (ST-246). Tecovirimat has low
Tecovirimat SIGA (marketed under the trade name TPOXX® in USA) is an oral medicine to treat smallpox, monkeypox and cowpox,
Product selection in the dynamic enzymatic synthesis of cyclodextrins can be controlled by changing the pH. Using cyclodextrin glucanotransferase to
Cyclodextrin-based polymers can be prepared starting from the naturally occurring monomers following green and low-cost procedures. They can be selectively
Octakis-6-guadinidino-γ-cyclodextrin (gguan) hydrochloride in the presence of phosphates crystallises from aqueous solution in the unprecedented form of a superdimer (dimer-within-a-dimer).
The polymerization of cyclodextrin (CD) with epichlorohydrin (ECH) dramatically increases the binding constant of CD to vanillin, from 55 to
In this work [1], (2-Hydroxypropyl)- β-cyclodextrin) fibres were successfully produced with water, as the “green” solvent with pressurised gyration and electrospinning,
The β-cyclodextrin derivatization with short oligoester chains, through convenient synthesis methods, leads to highly water-soluble and biodegradable compounds. Cyclodextrins have
The recently discovered molecular rotor and supravital dye, Basic Orange-21 (BO21), has shown improved differential counting of leukocytes through metachromasia
A research team consisting of scientists located in Spain and Denmark have successfully proven that the formation of inclusion complexes