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June 15, 2022 CD as API / Pharma applications / Uncategorized

Efficacy and safety of sugammadex for neuromuscular blockade reversal in pediatric patients: an updated meta-analysis of randomized controlled trials with trial sequential analysis

Background: A recent survey revealed that extensive off-label use of sugammadex in pediatric anesthesia deserved particular attention. The present study

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December 13, 2021 Uncategorized

Special Issue: Cyclodextrin applications in pharmacy, biology, medicine, and environment

This special Issue on “Cyclodextrin Applications in Pharmacy, Biology, Medicine and Environment” edited by Crini, G. and Aleya, L., consisted

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December 2, 2021 Uncategorized

Molecular interactions in remdesivir-cyclodextrin systems

In a recently published study intermolecular interactions of remdesivir and various cyclodextrin derivatives were characterized by extensive NMR spectroscopy. The

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November 22, 2021 Uncategorized

Use of cyclodextrins in diseases and disorders involving phospholipid dysregulation

A patent application by Knut M. Wittkowski (ASDERA LLC, US) entitled “Use of cyclodextrins in diseases and disorders involving phospholipid

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November 8, 2021 Uncategorized

Native Cyclodextrins and Their Derivatives as Potential Additives for Food Packaging: A Review

CDs and their inclusion complexes have been proposed to be used as potential allies in food packaging, especially in active

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October 28, 2021 CD as API / Drug delivery / Pharma applications / Uncategorized

METHYL-CYCLODEXTRIN FOR USE IN TREATING ENVELOPED VIRUS INFECTIONS SUCH AS SARS-CoV-2

The patent application (1) with priority date of 09. March 2020 claims that methyl bCD preferably with DS 0.7 (Crysmeb)

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September 27, 2021 Uncategorized

Caffeine, a natural methylxanthine nutraceutical, exerts dopaminergic neuroprotection

Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects more than 10 million people worldwide. Oxidative stress and mitochondrial

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August 6, 2021 Uncategorized

Extraction of mycotoxins from aqueous solutions using beta-cyclodextrin bead polymer

In previous studies, the extraction of mycotoxins alternariol, zearalenone, zearalenols, zearalenone-14-glucoside, and zearalenone-14-sulfate from aqueous solutions (including certain beverages) by

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July 21, 2021 Drug delivery / Pharma applications / Uncategorized

Intraoral/intranasal niclosamide/HPBCD formulation for treatment of COVID-19

A recently published patent of Union Therapeutics, Denmark (US11045434) (granted extremely rapidly by USPTO within 8 months from filing date)

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May 7, 2021 Food / Non-pharma applications / Uncategorized

CAVACURMIN®: Study Reveals Increased Metabolic Bioavailability of Tetrahydrocurcumin

A study recently published in the Journal of Functional Foods shows that ingestion of the curcumin-cyclodextrin complex CAVACURMIN® leads to an

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