CDs for Regulating Cholesterol Homeostasis in Atherosclerosis
The progression of atherosclerosis (AS) is strongly linked to lipid crystals accumulation caused by cholesterol metabolism disorders and the worsening
Tag: atherosclerosis
Multifunctional biomimetic nanocarriers for the treatment of atherosclerosis
Atherosclerosis (AS) has been considered a systemic disease characterized by the excessive generation of reactive oxygen species (ROS) and the
Selective removal of 7-ketocholesterol by a CD-dimer, a novel atherosclerosis therapeutic candidate
The removal of the toxic oxidized cholesterol, 7-ketocholesterol (7KC), from cells through the administration of therapeutics has the potential to
Targeted drug delivery systems for atherosclerosis
A review with 402 references Atherosclerosis is a complex cardiovascular disease driven by multiple factors, including aging, inflammation, oxidative stress,
Cyclodextrin Complexes: A New Hope Against Atherosclerosis
Recently, increasing evidence shows that cyclodextrins have an inhibitory effect against atherosclerosis, a chronic disease inducing atherosclerotic cardiovascular diseases (ASCVDs).
Cyclodextrin derivative developed by Cyclarity in clinical trial
Cyclarity Therapeutics is pleased to announce regulatory approval to begin its first-in-human clinical trial. The trial will be conducted at CMAX,
Technological trends in cyclodextrin inclusion complexes for improving cardiovascular drug therapy: A patent review,
Cardiovascular diseases are disorders that compromise the heart and circulatory systems. Ischemic heart disease is one of the causes of
The revival of cyclodextrins as active pharmaceutical ingredients
Cyclodextrins have long been known as host molecules, a special feature that has led to their widespread use in a
Cyclodextrins as therapeutic drugs for treating lipid metabolism disorders
This study sought to systematically compare the efficacy and mechanism of cyclodextrins as drug interventions in lipid metabolism diseases, potentially
Macrophage Membrane-Encapsulated Dopamine-Modified Poly Cyclodextrin Multifunctional Biomimetic Nanoparticles for Atherosclerosis Therapy
Atherosclerotic plaques exhibit high cholesterol deposition and oxidative stress resulting from high reactive oxygen species (ROS). These are the major