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Tag: atherosclerosis

June 17, 2024 Diagnosis / Pharma applications

CD-based diagnostic tool for atherosclerotic plaque

Atherosclerosis (AS), a pathological cause of cardiovascular disease, results from endothelial injury, local progressive inflammation, and excessive lipid accumulation. AS

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May 28, 2024 CD as API / Drug delivery / Pharma applications

Hemoperfusion with Chondroitin Sodium Sulfate/Cyclodextrin/Poly(acrylic acid) Composite Adsorbents for Atherosclerosis Therapy

Atherosclerosis (AS) is characterized by the accumulation of substantial low-density lipoprotein (LDL) and inflammatory response. Hemoperfusion is commonly employed for

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April 30, 2024 CD as API / Pharma applications / Uncategorized

Nanomedicine-based drug delivery strategies for the treatment of atherosclerosis

This review provides a comprehensive overview of emerging nanomedicine-based strategies for targeted delivery of anti-atherosclerosis drugs, elucidating their distinct mechanisms

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April 4, 2024 CD as API / Pharma applications

Cyclodextrins as therapeutic drugs for treating lipid metabolism disorders

This study sought to systematically compare the efficacy and mechanism of cyclodextrins as drug interventions in lipid metabolism diseases, potentially

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January 19, 2024 CD as API / Pharma applications

Cyclodextrin-loaded nanobubbles reduce cholesterol and atherosclerosis in vivo

Polymeric nanobubbles were prepared by using polybutlycyanoacrylate. The incorporation of near-infrared dye (IR780) resulted in a multimodal contrast NB, which

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October 3, 2023 CD as API

Cyclodextrin dimers against atherosclerosis

7-ketocholesterol (7-oxocholesterol, 7-KC) is the major oxidation product of cholesterol (CHOL), and one of the most toxic metabolites formed when

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September 28, 2023 CD as API / Drug delivery / Pharma applications

Biomimetic nanoparticles to enhance the reverse cholesterol transport for selectively inhibiting development into foam cell in atherosclerosis

A disorder of cholesterol homeostasis is one of the main initiating factors in the progression of atherosclerosis (AS). Metabolism and

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August 14, 2023 Drug delivery / Pharma applications

Recent Advances for Dynamic-Based Therapy of Atherosclerosis

Atherosclerosis (AS) is a chronic inflammatory disease, which may lead to high morbidity and mortality. Currently, the clinical treatment strategy

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December 1, 2022 CD as API / Pharma applications

Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?

In this review, based on 250 references, the general chemical principles of direct cyclodextrin–protein interactions are summarized and highlighted, through

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October 7, 2022 CD as API / Pharma applications / Supramolecular systems

Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis

A promising therapy for atherosclerosis treatment was designed by targeting LXR receptor (LXR) on atherosclerotic macrophage, where LXR activation could

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