Cyclodextrin-Based Oral Solution of Ursodeoxycholic Acid Using a Ready-to-Use Vehicle
Researchers from Italy and Argentina developed a HPBCD-based oral solution of ursodeoxycholic acid (UDCA), a bile acid widely used for
Tag: drug delivery
Cholesteryl Cyclodextrin for Enhanced Delivery of Doxorubicin and 5-Fluorouracil
This study (1) aims to build on previously published results that characterized cholesteryl-modified β-cyclodextrin (CD21chol) as a carrier for 5-fluorouracil. (2)
Cyclodextrin/Caffeic Acid Nanofibers
Two types of hydroxypropylated CD (HPβCD and HPγCD) were used to create electrospun nanofibers with two different molar ratios (1:1
CD-functionalized chitosan hydrogels for pH-responsive drug delivery
Traditional chitosan hydrogels are highly biocompatible but too hydrophilic to effectively load and sustain release of hydrophobic drugs. In a
Poly-CD-PEG-camptothecin Combined with Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer (Clinical trial)
The authors hypothesized that integrating tumor-targeted topoisomerase I inhibitor delivery with optimized PARP inhibitor scheduling could enable effective combination therapy
Cyclodextrin-based polymer materials and their applications – A review covering a 20-year period
Cyclodextrins (CDs) have undergone a remarkable evolution over the past three decades, transitioning from classical solubilizing agents to multifunctional platforms
Chitosan-coated cyclodextrin-based niosomes enable enhanced nose-to-brain delivery of rivastigmine and asiaticoside for Alzheimer’s disease
The co-delivery of rivastigmine hydrogen tartrate (RHT) and asiaticoside (AS) offers a promising strategy for enhancing acetylcholinesterase (AChE) inhibition in
Combined cyclodextrins and porphyrinoid derivatives in drug delivery systems
Porphyrins are powerful photosensitive molecules with useful photophysical and redox properties, making them attractive for therapeutic use. However, they often
Comparative Study of Nanosuspensions for Acetogenins Delivery
Researchers in Mexico compared two food-grade nanosuspension formulations for oral delivery of acetogenins (ACGs), a potent but poorly soluble class
Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
Fungal keratitis (FK) is a leading cause of corneal blindness worldwide. Although voriconazole (VOR) is effective, its poor corneal permeability