Sugammadex in Colorectal and da Vinci Surgery
Traditionally, reversal of neuromuscular blocking agents following the completion of surgery was achieved with cholinesterase inhibitors. Recently, sugammadex has been
Tag: Sugammadex
Molecular interactions in remdesivir-cyclodextrin systems
In a recently published study intermolecular interactions of remdesivir and various cyclodextrin derivatives were characterized by extensive NMR spectroscopy. The
Comparison of Selective Relaxant Binding Agent Adamgammadex Sodium with Sugammadex for Reversing Rocuronium-Induced Deep Neuromuscular Block
Zhao et al. reported on a phase IIa, single-center, randomized, open-label, and dose-finding study that enrolled 35 patients under general
Sugammadex, the Guardian of Deep Muscle Relaxation During Conventional and Robot-Assisted Laparoscopic Surgery: A Narrative Review.
High intra-abdominal pressure induced by artificial pneumoperitoneum can obviously impair respiratory and circulatory functions and has a negative effect on
Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study
Residual neuromuscular block at the end of surgery may compromise the patient’s safety. The risk of airway complications can be
Possible immunoglobulin-E-dependent sugammadex-induced anaphylaxis caused by an epitope other than γ-cyclodextrin: a case report
A 55-year-old Japanese man underwent a laryngectomy under general anesthesia. One month before laryngectomy, he had undergone laryngoscopy under general
Pillar[n]MaxQ: A New High Affinity Host Family for Sequestration in Water
Lyle Isaacs and his research team from the University of Maryland have further advanced the structure of the pillararenes to
Chlorpromazine complexation with Sugammadex – an extremely high complexation constant
An in press paper on detailed ITC and NMR study of chlorpromazin complexation with various cyclodextrins reports on an unexpected
Carbohydrate drugs (Part 5) (Oligosaccharides, cyclodextrins)
First let’s talk about one of the biggest achievements in the history of cyclodextrin research: Sugammadex. Sugammadex (SGM) (BridionTM) (1a)
Cyclodextrin News Year in Review 2018
The CDNews blog was created in July and after a short period of trial it started in September. During this