Neostigmine vs. sugammadex: on postoperative nausea and vomiting (PONV) after general anaesthesia
Sugammadex (SGM) is the first cyclodextrin derivative approved as an API, the result of a rational drug design, with a
A forum for researchers, students and applicants in the field of cyclodextrin technology
Sugammadex (SGM) is the first cyclodextrin derivative approved as an API, the result of a rational drug design, with a
The present contribution describes for the first time the application of three single-isomeric cyclodextrin derivatives – Sugammadex, Subetadex and Sualphadex
A meta-analysis has been recently published about the dosing of sugammadex (SGM) for neuromuscular blockade (NMB) induced muscle relaxation in
Background: A recent survey revealed that extensive off-label use of sugammadex in pediatric anesthesia deserved particular attention. The present study
Traditionally, reversal of neuromuscular blocking agents following the completion of surgery was achieved with cholinesterase inhibitors. Recently, sugammadex has been
In a recently published study intermolecular interactions of remdesivir and various cyclodextrin derivatives were characterized by extensive NMR spectroscopy. The
Zhao et al. reported on a phase IIa, single-center, randomized, open-label, and dose-finding study that enrolled 35 patients under general
High intra-abdominal pressure induced by artificial pneumoperitoneum can obviously impair respiratory and circulatory functions and has a negative effect on
Residual neuromuscular block at the end of surgery may compromise the patient’s safety. The risk of airway complications can be
A 55-year-old Japanese man underwent a laryngectomy under general anesthesia. One month before laryngectomy, he had undergone laryngoscopy under general