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Tag: Sugammadex

September 28, 2022 Analysis / CD derivatives / Non-pharma applications

Sugammadex, Subetadex and Sualphadex as chiral selectors

The present contribution describes for the first time the application of three single-isomeric cyclodextrin derivatives – Sugammadex, Subetadex and Sualphadex

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September 7, 2022 CD as API / Pharma applications

Appropriate Dosing of Sugammadex in Morbidly Obese Patients

A meta-analysis has been recently published about the dosing of sugammadex (SGM) for neuromuscular blockade (NMB) induced muscle relaxation in

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June 15, 2022 CD as API / Pharma applications / Uncategorized

Efficacy and safety of sugammadex for neuromuscular blockade reversal in pediatric patients: an updated meta-analysis of randomized controlled trials with trial sequential analysis

Background: A recent survey revealed that extensive off-label use of sugammadex in pediatric anesthesia deserved particular attention. The present study

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February 2, 2022 CD as API / Pharma applications

Sugammadex in Colorectal and da Vinci Surgery

Traditionally, reversal of neuromuscular blocking agents following the completion of surgery was achieved with cholinesterase inhibitors. Recently, sugammadex has been

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December 2, 2021 Uncategorized

Molecular interactions in remdesivir-cyclodextrin systems

In a recently published study intermolecular interactions of remdesivir and various cyclodextrin derivatives were characterized by extensive NMR spectroscopy. The

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September 28, 2021 CD as API / Pharma applications

Comparison of Selective Relaxant Binding Agent Adamgammadex Sodium with Sugammadex for Reversing Rocuronium-Induced Deep Neuromuscular Block

Zhao et al. reported on a phase IIa, single-center, randomized, open-label, and dose-finding study that enrolled 35 patients under general

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September 20, 2021 CD as API / Pharma applications

Sugammadex, the Guardian of Deep Muscle Relaxation During Conventional and Robot-Assisted Laparoscopic Surgery: A Narrative Review.

High intra-abdominal pressure induced by artificial pneumoperitoneum can obviously impair respiratory and circulatory functions and has a negative effect on

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August 24, 2021 CD as API / Pharma applications

Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study

Residual neuromuscular block at the end of surgery may compromise the patient’s safety. The risk of airway complications can be

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July 29, 2021 CD as API / CD derivatives / Pharma applications

Possible immunoglobulin-E-dependent sugammadex-induced anaphylaxis caused by an epitope other than γ-cyclodextrin: a case report

A 55-year-old Japanese man underwent a laryngectomy under general anesthesia. One month before laryngectomy, he had undergone laryngoscopy under general

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December 2, 2020 Pharma applications

Pillar[n]MaxQ: A New High Affinity Host Family for Sequestration in Water

Lyle Isaacs and his research team from the University of Maryland have further advanced the structure of the pillararenes to

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