Neostigmine vs. sugammadex: on postoperative nausea and vomiting (PONV) after general anaesthesia
Sugammadex (SGM) is the first cyclodextrin derivative approved as an API, the result of a rational drug design, with a
Tag: Sugammadex
Sugammadex, Subetadex and Sualphadex as chiral selectors
The present contribution describes for the first time the application of three single-isomeric cyclodextrin derivatives – Sugammadex, Subetadex and Sualphadex
Appropriate Dosing of Sugammadex in Morbidly Obese Patients
A meta-analysis has been recently published about the dosing of sugammadex (SGM) for neuromuscular blockade (NMB) induced muscle relaxation in
Efficacy and safety of sugammadex for neuromuscular blockade reversal in pediatric patients: an updated meta-analysis of randomized controlled trials with trial sequential analysis
Background: A recent survey revealed that extensive off-label use of sugammadex in pediatric anesthesia deserved particular attention. The present study
Sugammadex in Colorectal and da Vinci Surgery
Traditionally, reversal of neuromuscular blocking agents following the completion of surgery was achieved with cholinesterase inhibitors. Recently, sugammadex has been
Molecular interactions in remdesivir-cyclodextrin systems
In a recently published study intermolecular interactions of remdesivir and various cyclodextrin derivatives were characterized by extensive NMR spectroscopy. The
Comparison of Selective Relaxant Binding Agent Adamgammadex Sodium with Sugammadex for Reversing Rocuronium-Induced Deep Neuromuscular Block
Zhao et al. reported on a phase IIa, single-center, randomized, open-label, and dose-finding study that enrolled 35 patients under general
Sugammadex, the Guardian of Deep Muscle Relaxation During Conventional and Robot-Assisted Laparoscopic Surgery: A Narrative Review.
High intra-abdominal pressure induced by artificial pneumoperitoneum can obviously impair respiratory and circulatory functions and has a negative effect on
Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study
Residual neuromuscular block at the end of surgery may compromise the patient’s safety. The risk of airway complications can be
Possible immunoglobulin-E-dependent sugammadex-induced anaphylaxis caused by an epitope other than γ-cyclodextrin: a case report
A 55-year-old Japanese man underwent a laryngectomy under general anesthesia. One month before laryngectomy, he had undergone laryngoscopy under general