Bridging cyclodextrin to transfect siRNA
The bridging of beta-cyclodextrin with an ammonium linker which bears a hydrophobic substituent efficiently forms supramolecular polymers, avoiding the competing
Fraud companies infiltrating cyclodextrin business
I would like to draw your attention to a very recent desperate approach for taking advantage of one’s naivety and
Bridging cyclodextrin to transfect siRNA
The bridging of beta-cyclodextrin with an ammonium linker which bears a hydrophobic substituent efficiently forms supramolecular polymers, avoiding the competing
Amgen Submits Supplemental New Drug Application For KYPROLIS® (carfilzomib)
Amgen announced on the 27th August, 2018 the submission of a supplemental New Drug Application (sNDA) to the U.S. Food
Cyclodextrin-containing polymer-camptothecin nanopharmaceutical. Clinical trials
Cyclodextrin-containing polymer (CDP) (represented by blue in the scheme) conjugated to camptothecin (CPT) (represented by red) forms 30-40-nm diameter nanoparticles
HPBCD was tested for revealing the symptoms of Cockayne syndrome in mouse model: a surprise
Cockayne syndrome is a hereditary form of premature aging caused by a gene mutation. The disease affects more organs including
Cyclodextrin to formulate proteins – dream or reality
Several cyclodextrins have been claimed by dozens of papers including huge works of Serno [1] and Hartl [2] to be
Improved method for the preparation of SBECD – In which aspect?
Recently, a new patent application became accessible to the public, WO2018146698 (A1), filed by Biophore India, a DMF holder for the
Video-class on the effect of cyclodextrins on drug permeation through membranes
Prof. Thorsteinn Loftsson (University of Iceland) explains in his lecture on the website of CyclonHit project the mechanism how drugs
Video-class on the Effects of Cyclodextrins on Drug Stability
The video of Prof. Thorsteinn Loftsson on the website of CyclonHit project gives the basic information on the effect of
Video-class on Cyclodextrins as Solubilizers
The video of Prof. Thorsteinn Loftsson shows how to perform solubility studies, the types of phase-solubility isotherms, continuous variation plots