Potential Glioblastoma Therapy with Cationic Cyclodextrin Polymers as Drug Delivery Excipients
Glioblastoma (GB) is the most common and aggressive malignant brain tumor, with a median survival of only 12–15 months despite
Potential Glioblastoma Therapy with Cationic Cyclodextrin Polymers as Drug Delivery Excipients
Glioblastoma (GB) is the most common and aggressive malignant brain tumor, with a median survival of only 12–15 months despite
Recent papers on Cyclodextrins in Nature
In Scientific Reports, a Japanese team investigated these effects for α-CD derivatives with various replaced substituents from the perspective of
Cantrixil: Advancing a Molecule’s Career with a Cyclodextrin Carrier
The success story of Cantrixil, a potent anti-cancer drug candidate, has been followed on our blog for years, and now
Oculis: eye drops with Dexamethasone/gamma-CD complex Phase 3 study concluded soon
Oculis’s most advanced product candidate, OCS-01, is currently in Phase 3 development and aims to be the first eye drop
Understanding DNA as Carrier of Drug/Cyclodextrin complex
The adsorption of drugs and their carriers onto double-stranded DNA is potentially significant for their transport and release within cells,
Special issue: New Insights into Cyclodextrin-Based Drug Delivery Systems
In recent decades, the biomedical and pharmaceutical potential of cyclodextrins has expanded remarkably. Their well‑established host–guest complexation ability continues to
Evaluation of the Potential Therapeutic Effects of HPβCD and SBEβCD in a Mouse Model of Acute Ulcerative Colitis
A Nanjing, China based research group designed a tailored investigation [1] based on a surprising previous study [2]. In they
HPBCD accesses acute and subacute infarcts in a mouse model of ischemic stroke
Ischemic stroke is a leading cause of mortality and long-term disability worldwide, with limited pharmacological interventions available. Researchers in Arizona
Flame-Resistant 3D Printing with Cyclodextrin: A Hewlett-Packard Patent Application
Hewlett-Packard has developed a multi-fluid kit for three-dimensional printing, comprising:– a fusing agent including: – an electromagnetic energy absorber; and
HPαCD Therapy: A Breakthrough for Krabbe Disease Treatment
Several North-American Universities worked together to find hydroxzpropyl-alpha-cyclodextrin(HPaCD) for the treatment of Krabbe disease. The deficiency of β-galactosylceramidase causes a