Fast-Dissolving Cyclodextrin Nanofibers for Pain Relief
A fast-dissolving nanofibrous film based on cyclodextrin (hydroxypropyl-β-cyclodextrin) inclusion complexes (ICs) incorporating a triple drug combination of acetylsalicylic acid (Aspirin),
Category: Pharma applications
Enhancing Linezolid Solubilization with β-Cyclodextrin Polymer Fractions of Different Molecula Weight
Epichlorohydrin-crosslinked β-cyclodextrin polymers (pCDs) are versatile drug carriers that solubilize poorly water-soluble molecules and exhibit intrinsic biological activity. However, the
Book chapter: Functionalized cyclodextrins in drug delivery
The book : Engineered Biomaterials for Drug Delivery (Edited by: Amit Kumar Nayak, Md Saquib Hasnain and Tejraj M. Aminabhavi)
β-Cyclodextrin-Complexed 1,8-Cineole Attenuates Motor Deficits and Preserves Tyrosine Hydroxylase Immunoreactivity in a Reserpine-Induced Mouse Model of Parkinsonism
Researchers from Brazil 🇧🇷 tested βCD-complexed 1,8-cineole (Eucalyptol) in mice with Parkinson-like symptoms. Daily treatment reduced tremors and other movement
Disruption of endosomal transport in cyclodextrin-mediated cytotoxicity
While β-cyclodextrins are commonly associated with cholesterol extraction, it remains unclear whether this mechanism alone explains their biological activity. Here,
New Hungarian Medicine on the Horizon?
Motorpharma Ltd., a Hungarian biotechnology company, has developed a number of promising experimental drugs targeting the motor proteins (e.g. myosins)
Rafael Holdings Announced Submission of New Drug Application to FDA for Trappsol®Cyclo™ (remibetadex) for the Treatment of Niemann-Pick Disease Type C
Rafael Holdings, Inc. (NYSE: RFL) announced on Oct. 29 that its subsidiary, Cyclo Therapeutics, LLC, has submitted a New Drug
New book on cyclodextrin glucanotransferase
A Comprehensive Guide from Gene to Applications Cyclodextrin Glucanotransferase: A Comprehensive Guide from Gene to Applications explores the essential role
Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
In this contribution, we report the design, synthesis, photochemical characterization, and biological validation of a novel, photoresponsive β-cyclodextrin branched polymer
Innovative Titanium Coatings for Enhanced Dental Implants
Researchers from Brazil and Switzerland developed a multifunctional coating for titanium dental implants that combines tetracycline complexed with anionic βCD