HPBCD is a unique component in Janssen’s COVID-19 vaccine candidate
Amongst Janssen’s novel single-dose Covid-19 vaccine candidate of adenovirus platform excipients one might notice a peculiar compound: Hydroxypropyl Betadex (HPBCD).
Category: Pharma applications
Effect of buffers on the stability of SBECD complexes
The effect of 11 buffers as well as the effect of ionic strength were investigated on the binding between the
New approach in ocular drug delivery: cyclodextrin-containing mucoadhesive eye drop formulations
In this study, prednisolone-containing ophthalmic formulations were developed with expected optimal permeation without toxic or irritative effects. The toxicity and
Cochlear spiral ganglion neuron degeneration following cyclodextrin-induced hearing loss
HPβCD as a treatment for Niemann-Pick Type C1 disease can reduce some debilitating symptoms and extend life span, but the
NIH funds study to evaluate remdesivir for COVID-19 in pregnancy
A new study funded by the National Institutes of Health will evaluate the effects of remdesivir in pregnant women who
The use of β-CDs to improve honey bee health
Honey bees are essential members of the natural ecosystems and the modern agriculture, yet their colonies are collapsing worldwide. In
Gd(3+) Complexes Conjugated to Cyclodextrins
In the search for improvement in the properties of gadolinium-based contrast agents, cyclodextrins (CDs) are interesting hydrophilic scaffolds with high
Reviews on remdesivir in Covid-19 treatment
Remdesivir (GS-5734; Gilead Sciences Inc., US) is an investigational nucleoside analog that acts as a competitive inhibitor of viral RNAdependent
4th China International BioPharma Conference & Exhibition
2021 China International BioPharma Conference will be held on September 19th-21th in China Medical City Convention and Exhibition Center, Taizhou China.
Cyclo Therapeutics Presents Positive Data from Clinical Development Program for Lead Candidate, Trappsol® Cyclo™, at WORLDSymposium 2021
Cyclo Therapeutics, Inc., a clinical stage biotechnology company developing cyclodextrin-based products for the treatment of Niemann-Pick Disease Type C and