Cyclodextrin dimers against atherosclerosis
7-ketocholesterol (7-oxocholesterol, 7-KC) is the major oxidation product of cholesterol (CHOL), and one of the most toxic metabolites formed when
Category: Pharma applications
Cyclodextrin related patent application of 2023 Nobel laureate Katalin Karikó
This year’s Nobel Prize in physiology or medicine has been awarded to Katalin Karikó and Drew Weissman for their work
Cyclodextrin in Vaccines
Cyclodextrins, have emerged as a focal point of interest within the pharmaceutical realm, owing to their distinctive molecular structure and
Biomimetic nanoparticles to enhance the reverse cholesterol transport for selectively inhibiting development into foam cell in atherosclerosis
A disorder of cholesterol homeostasis is one of the main initiating factors in the progression of atherosclerosis (AS). Metabolism and
Ex Vivo Drug Screening Assay with Artificial Membranes: Characterizing Cholesterol Desorbing Competencies of Beta-Cyclodextrins
Despite advancements in contemporary therapies, cardiovascular disease from atherosclerosis remains a leading cause of mortality worldwide. Supported lipid bilayers (SLBs)
Cytotoxicity of 5-Fluorouracil- Loaded, β-Cyclodextrin-Tethered Metallic Copper Nanoparticles on Triple-Negative Breast Cancer Cells
Metal nanoparticles represent simple nanoscale structures that can be employed in drug delivery. The complication due to multiple elements in
Application of Cyclodextrin for Cancer Immunotherapy
Tumor immunotherapy, compared with other treatment strategies, has the notable advantage of a long-term therapeutic effect for preventing metastasis and
Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment
Cyclodextrins (CDs), the therapeutic candidates for Niemann–Pick disease type C (NPC), function dually as a shuttle and sink that catalytically
PhD and post-doctoral fellowships
Up to 12 fully funded PhD positions have been offered to highly motivated and talented researchers at the Cologne Graduate
Curcumin/amphiphilic cyclodextrin nanoassemblies: Theoretical andspectroscopic studies to address their debut in anticancer therapy
Curcumin and its derivatives have been extensively used as natural adjuvants in different pathologies including cancer, cardiovascular disease, Alzheimer’s disease,