FDA Issues Emergency Use Authorization for Third COVID-19 Vaccine
As we reported on CDN blog FDA approval for Janssen vaccine containing HPBCD was expected in late February. The Janssen
Category: Pharma applications
Improving Bioavailability & Solubility
Drug Development & delivery published on the virtual 2020 Global Drug Bioavailability Enhancement Summit, which this past December showcased novel
Heptakis(6-amino-6-deoxy)-beta-cyclodextrin stabilizes the synthetic anticoagulant fondaparinux
The intermolecular interactions between the cationic per-6-amino-b-CD with the highly anionic heparin analogue anticoagulant fondaparinux were studied at two different
KAZIA LICENSES CANTRIXIL TO OASMIA
Kazia Therapeutics Limited, an Australian oncology-focused biotechnology company, announced that it has entered into an exclusive worldwide license agreement with
Aerogels in drug delivery. Review
Aerogels are the lightest processed solid materials on Earth and with the largest empty volume fraction in their structure. Composition
HPBCD is a unique component in Janssen’s COVID-19 vaccine candidate
Amongst Janssen’s novel single-dose Covid-19 vaccine candidate of adenovirus platform excipients one might notice a peculiar compound: Hydroxypropyl Betadex (HPBCD).
Effect of buffers on the stability of SBECD complexes
The effect of 11 buffers as well as the effect of ionic strength were investigated on the binding between the
New approach in ocular drug delivery: cyclodextrin-containing mucoadhesive eye drop formulations
In this study, prednisolone-containing ophthalmic formulations were developed with expected optimal permeation without toxic or irritative effects. The toxicity and
Cochlear spiral ganglion neuron degeneration following cyclodextrin-induced hearing loss
HPβCD as a treatment for Niemann-Pick Type C1 disease can reduce some debilitating symptoms and extend life span, but the
NIH funds study to evaluate remdesivir for COVID-19 in pregnancy
A new study funded by the National Institutes of Health will evaluate the effects of remdesivir in pregnant women who