Nano-formulations containing SBECD
Various nano-formulations containing SBECD have been studied in order to utilize the inclusion complex forming (solubilizing, stabilizing) ability of this
Category: Pharma applications
Clinical trial: Allopregnalonone/Dexolve for Post Traumatic Stress Disorder
About 6.4% of the U.S. population suffers from posttraumatic stress disorder (PTSD). Trauma-focused psychotherapies are generally effective in PTSD, but
Hot-melt extrusion for cyclodextrin inclusion complex of a multicomponent natural product
This study aimed to investigate whether hot-melt extrusion (HME) processing can promote molecular encapsulation of a multi-component natural product composed
Ensemble Simulations of 2-Hydroxypropyl-β-cyclodextrin Complexes with All-Atom Molecular Dynamics Simulations
2-Hydroxypropyl-β-cyclodextrins (HP-β-CDs) ability to form inclusion complexes with lipophilic compounds is important both to treat Niemann Pick Type C disease
Electrospun nanofibrous membrane functionalized with dual drug-cyclodextrin inclusion complexes as otic formulations for the potential treatment of otitis externa
External ear canal infections and inflammation (called otitis externa) represent considerable health and psychological problem. It is commonly treated via
Hyaluronic acid-cyclodextrin conjugate encapsulating paeonol for treatment of atopic dermatitis
CD was grafted onto hyaluronic acid (HA) to form a topical delivery carrier (HACD) in which Paeonol was loaded in
Special Issue: Supramolecular Systems for Gene and Drug Delivery (Volume II)
Special Issue: Supramolecular Systems for Gene and Drug Delivery (Volume II) has been anounced in the journal Pharmaceutics which has just
Integration of cyclodextrins and associated toxicities: A roadmap for high quality biomedical applications
Cyclodextrins are extensively employed in drug delivery systems like inclusion complexes, metal-organic frameworks, functionalized or PEGylated conjugates, and other nanocarrier
HPaCD against Alzheimer Disease
HP-beta-cyclodextrin (HPbCD) is currently in clinical trials against Niemann-Pick Disease Type C (NPC) and Alzheimer’s Disease (AD) and these trials
Cyclodextrin in tissue engineering
The field of tissue engineering continues to advance, sometimes in exponential leaps forward, but also sometimes at a rate that