5th International Conference Integrative Chemistry, Biology & Translational Medicine
The conference will be held on 25-27 June 2026 in Debrecen. The journey of ICBTM began in 2019 with the
Category: Pharma applications
Cyclodextrin Polymer Complexation Improves the Tolerability of Parenteral Oestradiol
This study investigates the PEG‑β‑CD polymer, a water‑soluble polyethylene glycol–β‑cyclodextrin cross‑linked carrier, as a potential alternative to conventional oestradiol formulations
The mechanism of ototoxicity studied by using HPBCD
The cochlea is the sensory organ responsible for hearing. Central to its sensory functions is the organ of Corti, a
Enhancing the Water Solubility and Efficacy of Anticancer Drugs Using Hydroxypropyl-β-Cyclodextrin
Previous studies have demonstrated that the solubility and biocompatibility of poorly water-soluble anti-cancer agents can be improved by complexation with
Dimethylated β-cyclodextrin inclusion complexes containing the guest steroid hormones progesterone and 17β-estradiol: syntheses, crystal structures, thermal analyses and steroid solubility enhancements
The aim of the present study was to complex the potent steroidal hormones progesterone (PRO) and 17β-estradiol (BES) with heptakis(2,6-di-O-methyl)-β-cyclodextrin
New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA
VYKOURA is a newly approved medication (marketing start date: 02/03/2026) containing leucovorin calcium, a prescription injectable drug used in hospital
Betadex sulfobutylether sodium — a key enabler for potent neurotherapeutics
In the search for better therapies for neurodegenerative diseases like Parkinson’s, researchers are increasingly looking beyond classical drugs to the
Sulfated β-Cyclodextrin-Mediated Antimicrobial Peptide Nanoparticles for Alkaloid Encapsulation
The β-cyclodextrin bearing an average of 13 sulfate groups (S13βCD) uniquely combines two key functions: it binds pharmaceutically relevant alkaloids
CDs for Regulating Cholesterol Homeostasis in Atherosclerosis
The progression of atherosclerosis (AS) is strongly linked to lipid crystals accumulation caused by cholesterol metabolism disorders and the worsening
Remdesivir (GS-5734) protects African green monkeys (AGM) from Nipah virus challenge
Introduction: Nipah virus is an emerging pathogen in the Paramyxoviridae family, which appers today a real threat for eventual pandemy.