Cyclodextrin-Based Niosomal Delivery of Imatinib
Lung cancer remains a significant cause of cancer-related deaths globally. The effective cancer treatment aims to deliver drugs that specifically
Category: Pharma applications
pH-responsive magnetic cyclodextrin-liposome nanoplatforms for stabilization and targeted delivery of topotecan
Topotecan (TPT), a potent anticancer agent, suffers from rapid hydrolysis of its active lactone ring under physiological conditions, severely limiting
Sugammadex vs. Neostigmine Reversal After Thoracoscopic Thymectomy in Myasthenia Gravis
Rapid and complete reversal of residual neuromuscular blockade (rNMB) is essential for safe postoperative recovery in patients with myasthenia gravis
Cyclodextrin-Driven Drug Deaggregation
The poor aqueous solubility of niclosamide (Nic), a drug with broad therapeutic potential beyond its original antiparasitic use, presents a
Special Issue of the 21st International Cyclodextrin Symposium
The papers from the Special Issue of the 21st International Cyclodextrin Symposium published in Carbohydrate Polymers are available (https://www.sciencedirect.com/special-issue/10BLTS8S758). The
Hydroxypropyl-Beta-Cyclodextrin (HPBCD) inhibits SARS-CoV-2 replication by modulating intracellular lipid dynamics
A multi-year scientific collaboration between Brasilian and American scientists from Federal University at Rio de Janeiro, Brazil, Laboratory of Immunoregulation,
HPBCD in liquid formulations: a systematic study of physical properties and surfactant compatibility
The researchers of TEVA (USA) explored the role of 2-hydroxypropyl-β-cyclodextrin (HPβCD) as an excipient in liquid formulations by evaluating its
Sulfonated, sulfated thioglycosides and multivalence in heparanase inhibition
Heparan sulfate (HS) analogs are synthetic oligo- and polysaccharides designed to mimic or enhance several biological properties of native HS.
2,6‑di‑O‑methyl‑3‑acetyl‑β‑cyclodextrin: a novel approach to reducde infectivity of SARS‑CoV‑2 and Japanese encephalitis virus
Among 19 CD derivatives studied, pretreatment of viral particles with DMA-β-CyD significantly reduced infectivity (by 2.25–2.67 log₁₀ units after 180
Neuroprotective effects of statins and cyclodextrins: review and potential role in dementia treatment
Dementia is a progressive and irreversible deterioration in cognition that has a significant impact on the person’s activities of daily