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Category: Pharma applications

February 19, 2026 CD as API / Drug delivery / Pharma applications

Enhancing the Water Solubility and Efficacy of Anticancer Drugs Using Hydroxypropyl-β-Cyclodextrin

Previous studies have demonstrated that the solubility and biocompatibility of poorly water-soluble anti-cancer agents can be improved by complexation with

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February 18, 2026 Drug delivery / Pharma applications

Dimethylated β-cyclodextrin inclusion complexes containing the guest steroid hormones progesterone and 17β-estradiol: syntheses, crystal structures, thermal analyses and steroid solubility enhancements

The aim of the present study was to complex the potent steroidal hormones progesterone (PRO) and 17β-estradiol (BES) with heptakis(2,6-di-O-methyl)-β-cyclodextrin

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February 17, 2026 CD derivatives / Drug delivery / Pharma applications

New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA

VYKOURA is a newly approved medication (marketing start date: 02/03/2026) containing leucovorin calcium, a prescription injectable drug used in hospital

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February 12, 2026 CD derivatives / Drug delivery / Life sciences / Pharma applications

Betadex sulfobutylether sodium — a key enabler for potent neurotherapeutics

In the search for better therapies for neurodegenerative diseases like Parkinson’s, researchers are increasingly looking beyond classical drugs to the

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February 10, 2026 CD derivatives / Drug delivery / Pharma applications

Sulfated β-Cyclodextrin-Mediated Antimicrobial Peptide Nanoparticles for Alkaloid Encapsulation

The β-cyclodextrin bearing an average of 13 sulfate groups (S13βCD) uniquely combines two key functions: it binds pharmaceutically relevant alkaloids

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February 9, 2026 CD as API / Drug delivery / Pharma applications

CDs for Regulating Cholesterol Homeostasis in Atherosclerosis

The progression of atherosclerosis (AS) is strongly linked to lipid crystals accumulation caused by cholesterol metabolism disorders and the worsening

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February 5, 2026 Drug delivery / Pharma applications

Remdesivir (GS-5734) protects African green monkeys (AGM) from Nipah virus challenge

Introduction: Nipah virus is an emerging pathogen in the Paramyxoviridae family, which appers today a real threat for eventual pandemy.

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February 4, 2026 CD as API / CD derivatives / Pharma applications

Studies on Sleep-Deprived Animals Reveal HPBCD’s Role in Restoring Normal Neuronal Function

A study published in Proceedings of the National Academy of Sciences (https://www.pnas.org/doi/10.1073/pnas.2523438123) suggests that lack of sleep harms the fatty insulation that

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February 2, 2026 Drug delivery

Subcutaneous injection of an SBECD salt of ketamine

Conventional ketamine hydrochloride solutions are acidic and hyperosmotic, limiting their tolerability for subcutaneous (SC) delivery. BB106 is a novel ketamine

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January 29, 2026 Drug delivery / Pharma applications

Poly(β-cyclodextrin)-coated dysprosium-doped ZnS nanocarriers

This study provides a comprehensive analysis of the structures and properties of zinc sulfide (ZnS) and dysprosium-doped ZnS nanoparticles (NPs)

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Recent Posts

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  • Poly-CD-PEG-camptothecin Combined with Olaparib  in People With Relapsed/​Refractory Small Cell Lung Cancer (Clinical trial)

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  • A review on sodium sulfobutylether-β-cyclodextrin (SBECD)
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