Carvone derived cannabidiol enantiomers as novel anticonvulsants
Developmental epilepsy syndromes are characterized by recurrent seizures and developmental delays. Current anticonvulsants target γ-aminobutyric acid type A receptor signaling
Category: Pharma applications
Amitriptyline in reducing bronchoconstriction effects compared to methyl BCD
Bronchial asthma is a chronic inflammatory disease with rising prevalence worldwide. Apart from the immunological role of the tricyclic antidepressant
Rotaxanes with integrated photoswitches: design principles, functional behavior, and emerging applications
Integrating molecular photoswitches into rotaxanes offers unique opportunities for precise control over their structural, dynamic, and functional properties. By harnessing
Cyclodextrins as Active Therapeutic Agents: Beyond Their Role as Excipients
Cyclodextrins (CDs) have traditionally been recognized as excipients that enhance solubility and stability of drugs. However, growing evidence shows that
Polyphenols’ encapsulation in cyclodextrins: An updated systematic literature review
Polyphenols are phytochemicals derived from fruits, leaves, flowers, roots, and other parts of various plants and other natural resources. These
Methyl BCD-based supramolecular polyrotaxane as theranostic in anticancer immunotherapy
Despite the tremendous therapeutic promise of activating stimulators of interferon genes (STING) enable to prime robust de novo T-cell responses,
Cyclodextrin complexation of selected tyrosine kinase inhibitors
The comprehensive physicochemical characterization and cyclodextrin complexation of four tyrosine kinase inhibitors — erlotinib, gefitinib, vandetanib, and lapatinib — were
Cyclodextrin-in-Liposome for therapy: Advances and challenges
The concept of drug-in-cyclodextrin-in-liposomes (DCLs) was introduced to the scientific community thirty years ago by McCormack and Gregoriadis (1994). Since
Thymol/gallic acid/β-cyclodextrin bio-nanocomposite against quorum sensing system and biofilm formation in P. aeruginosa (PAO1)
The quorum sensing (QS) system and cell-to-cell communication have had a significant impact on biofilm formation and virulence factor increase
Impact of Randomly Methylated Cyclodextrins on Candida albicans
The challenges related to biofilm-associated infections and diseases have prompted scientists to develop strategies aimed at reducing biofilm-forming capacity. Cells