Selective removal of 7-ketocholesterol by a CD-dimer, a novel atherosclerosis therapeutic candidate
The removal of the toxic oxidized cholesterol, 7-ketocholesterol (7KC), from cells through the administration of therapeutics has the potential to
Category: Pharma applications
A host-guest mediated immunomodulatory hydrogel with sustained antibacterial activity for healing of infected diabetic wounds
To solve the hinderance of infected diabetic wound regeneration and healing, an antibacterial and immunomodulatory hydrogel based on host-guest mediated
Dual activity of low-molecular-weight polymeric β-cyclodextrins against tuberculosis
/The biological properties of pβCD of different molecular weights were studied. Strikingly, only the low-molecular-weight pβCD (LMW-pβCD) displayed antibacterial activity,
Biomimetic cyclodextrin enzyme models for modulation of P. aeruginosa quorum sensing and host immune response
Quorum sensing (QS) is the cell-to-cell communication on cell density, which is based on signal molecules, N-acyl-homoserine lactones (AHLs) for
Fungal quorum sensing molecules as potential drugs in the treatment of chronic wounds and their delivery
Interestingly fungal quorum sensing signal molecules (QSMs) were found effective against bacterial biofilms hindering the healing of chronic non-healing wounds
Novel delivery systems for Resveratrol
A novel polymer, β-cyclodextrin-epichlorohydrin-cyanoguanidine polymer (CDPC) was synthesized to evaluate its potential as an efficient carrier for the encapsulation of
First EMA regulation on the residues of betadex sulfobutylether sodium in foodstuffs of animal
Regulation (European Commission) No. 470/2009 lays down Community procedures for the establishment of residue limits of pharmaceutical active substances, excipients
From an Idea to a Journey: My Path Toward Treating Gout and Hyperuricemia With Cyclodextrins
When I look back at the last few years, it’s hard not to feel moved by what this project has
Beta-cyclodextrin/salicylic acid complex in pads for wart treatment
A novel product labeled as “SottSunFeli Maximum strength wart remover patches” containing beta-cyclodextrin and 30% salicylic acid as active ingredient
Cyclodextrin-assisted drug delivery to Central Nervous System: Mavenclad™ for multiple sclerosis treatment
In a recent study, Professors Bodor and Buchwald review the use of cyclodextrin-enabled formulations to develop oral tablets of cladribine