Unexpected synergistic drug solubilization with γ-CD/phosphoric acid and γ-CD/maleic acid
Dovitinib has been investigated as an anti-tumor drug due to its ability to inhibit multiple receptor tyrosine kinases. Dovitinib free
Category: Pharma applications
Dramatically Increased Binding Constant of Water-Soluble Cyclodextrin Hyperbranched Polymers
The polymerization of cyclodextrin (CD) with epichlorohydrin (ECH) dramatically increases the binding constant of CD to vanillin, from 55 to
Strategies to Improve Drug Strength in Nasal Preparations for Brain Delivery of Low Aqueous Solubility Drugs
Intranasal administration is a promising route for brain drug delivery. However, it can be difficult to formulate drugs that have
Three Birds, One Excipient: Development of an Improved pH, Isotonic, and Buffered Ketamine Formulation for Subcutaneous Injection
Subcutaneous (SC) ketamine has been found to be effective in pain management, though reports of injection site irritation and sterile
Sulfobutylation of Beta-Cyclodextrin Enhances the Complex Formation with Mitragynine: An NMR and Chiroptical Study
Mitragynine (MTR), the main indole alkaloid of the well-known plant kratom (Mitragyna speciosa) is a partial agonist on the opioid
Use of Antivirals in SARS-CoV-2 Infection. Critical Review of the Role of Remdesivir
The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of
Complexation of phytochemicals with cyclodextrins and their derivatives- an update
Bioactive phytochemicals from natural source have gained tremendous interest over several decades due to their wide and diverse therapeutic activities
Computational Modeling on Binding Interactions of Cyclodextrins with the Human Multidrug Resistance P-glycoprotein
Molecular docking approaches and DFT ab initio simulations were combined for the first time, to study the key interactions of
Promising results of sulfobutylether-β-cyclodextrin based low-melting mixture in the solubilization of steroids
Encapsulation in cyclodextrins (CDs) and solvation in deep eutectic solvents (DESs) are both efficient strategies for the solubilization of poorly
Special Issue: Cyclodextrins and Their Inclusion Complexes for Pharmaceutical Uses
Special Issue will be published in Pharmaceutics on Cyclodextrins and Their Inclusion Complexes for Pharmaceutical Uses. This Special Issue will