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June 29, 2022 Events / Non-pharma applications / Pharma applications

Special issue: Recent Insights in Chemistry and Technology of Cyclodextrins

International Journal of Molecular Sciences (MDPI) plans a Special Issue: Recent Insights in Chemistry and Technology of Cyclodextrins in connection

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June 27, 2022 CD derivatives / Gene delivery / Supramolecular systems

Matthieu SOLLOGOUB at ICS 20

Matthieu Sollogoub, professor of Biological and Supramolecular Glycochemistry at Sorbonne University gave a plenary lecture at the 20th International Cyclodextrin

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June 27, 2022 Events

CicloTech®, a new platform to improve trans-ungual drug release

CicloTech® is a nail lacquer platform based on thermosensitive hydrogels elaborated with mixtures of soluble pseudopolyrotaxans of poloxamers and beta-cyclodextrin

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June 3, 2022 Food / Non-pharma applications

Application of starch-based nanoparticles and cyclodextrin for prebiotics delivery and controlled glucose release in the human gut: a review

Starches are a major constituent of staple foods and are the main source of energy in the human diet (55-70%).

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June 2, 2022 CD derivatives / Gene delivery / Pharma applications

Tetraethylenepentamine-Coated β Cyclodextrin Nanoparticles for Dual DNA and siRNA Delivery

Tetraethylenepentamine-coated β-cyclodextrin (TEPA-BCD) nanoparticles were synthesized, characterized, and evaluated for targeted cell delivery of plasmid DNA and siRNA. The cationic

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June 1, 2022 CD as API / Pharma applications

Brain uptake and distribution patterns of 2-hydroxypropyl-ß-cyclodextrin after intrathecal and intranasal administration

2-hydroxypropyl-ß-cyclodextrin (kleptose) is used for the treatment of Niemann–Pick disease. Kleptose crosses the blood–brain barrier poorly, in part because of

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May 31, 2022 Analysis / CD derivatives / Non-pharma applications

Enhanced Chiral Recognition Abilities of Cyclodextrin Covalent Organic Frameworks via Chiral/Achiral Functional Modification

β-Cyclodextrin covalent organic frameworks (β-CD COFs) show great potential in enantioseparation due to their uniformly distributed chiral recognition sites and

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May 31, 2022 Analysis / Non-pharma applications

The role of deep eutectic solvents in chiral capillary electrokinetic chromatography: a comparative study based on α-cyclodextrin chiral selector

Deep eutectic solvents (DESs) are emerging as potential candidates as additives/modifiers in chiral electrokinetic chromatography (EKC). However, the true role

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May 30, 2022 Drug delivery / Pharma applications

Poly(pseudo)rotaxanes formed by mixed micelles and α-cyclodextrin for drug delivery to the nail

This work aimed to develop water-based formulations for onychomycosis topical treatment using micelles of small pegylated surfactants associated with α-cyclodextrin

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May 27, 2022 Drug delivery / Pharma applications

Insulin Complexation with Cyclodextrins—A Molecular Modeling Approach

Around 5% of the population of the world is affected with the disease called diabetes mellitus. The main medication of

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May 26, 2022 CD derivatives / Drug delivery / Pharma applications

Update: FDA approves HPBCD-enabled tecovirimat against pox virus

As reported earlier Siga Technologies filed a patent application in the USA describing cyclodextrin solubilized tecovirimat (ST-246). Tecovirimat has low

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May 26, 2022 CD derivatives / Drug delivery / Pharma applications

Life cycle of Tecovirimat authorized to treat human monkeypox infection in EU has been extended by reformulation with HPBCD by the originator Siga Technologies.

Tecovirimat SIGA (marketed under the trade name TPOXX® in USA) is an oral medicine to treat smallpox, monkeypox and cowpox,

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May 26, 2022 CD derivatives

pH-Responsive templates modulate the dynamic enzymatic synthesis of cyclodextrins

Product selection in the dynamic enzymatic synthesis of cyclodextrins can be controlled by changing the pH. Using cyclodextrin glucanotransferase to

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  • Matthieu SOLLOGOUB at ICS 20
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  • Prof. Kohzo Ito at ICS 20

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