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April 8, 2021 CD as API / CD derivatives / Drug delivery / Pharma applications

Cyclodextrins in Antiviral Therapeutics and Vaccines

The review of Braga et al. describes the various roles of cyclodextrins (CDs) in vaccines againstviruses and in antiviral therapeutics

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April 7, 2021 CD derivatives / Drug delivery

FDA granted accelerated approval to umbralisib / HPBCD tablet

The Food and Drug Administration granted accelerated approval to umbralisib (Ukoniq, TG Therapeutics), a kinase inhibitor including PI3K-delta and casein

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April 6, 2021 CD derivatives / Food

Encapsulation of menthol into cyclodextrin metal-organic frameworks

Cyclodextrin (CD)-metal-organic frameworks (MOFs) are developed as a new type of food-acceptable multi-porous material, which shows a great potential for

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March 16, 2021 Drug delivery / Pharma applications

Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2

Drug combination strategies of repurposed drugs offer a number of advantages to monotherapies including the potential to achieve greater efficacy,

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March 15, 2021 CD derivatives / Drug delivery / Pharma applications

Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery

Thiolated β-cyclodextrin (β-CD) has the potential to enhance mucoadhesive and permeation enhancing properties on ocular mucosa. Thiolated β-CD was synthesized via replacement

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March 12, 2021 Drug delivery / Pharma applications

An interesting hypothesis: CD‐sACE2 inclusion compounds to treat COVID‐19

Angiotensin‐converting enzyme 2 (ACE2) has been identified as the main receptors for SARS‐CoV and SARS‐CoV‐2. Soluble ACE2 (sACE2) can bind

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March 11, 2021 CD as API / Pharma applications

α-cyclodextrin-based polyrotaxanes for tissue engineering

Photo-crosslinkable polyrotaxanes (PRXs) via riboflavins (RBFs) were designed for anchoring to biological tissues. In particular, PRXs with amino groups, in

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March 10, 2021 Agriculture / Non-pharma applications

Controlled release formulation of dimethyldisulfide antifungal agent

DMDS is a natural biological pesticide formed by the decomposition of soil fungi and bacteria. It controls soil nematodes and

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March 9, 2021 Environmental / Non-pharma applications

Environmental Applications of CD-Modified Hemp-Based Felts

In a study, an adsorption process using hemp-based materials in felt form was applied to remove between 45 and 53

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March 8, 2021 CD as API / CD derivatives / Pharma applications

Polycationic cyclodextrin nanoparticles induce apoptosis and affect antitumoral activity

Hepatocellular carcinoma (HCC) is a highly metastatic primary liver cancer generating molecular alterations that end up escaping the apoptotic machinery

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March 5, 2021 Events

World Congress & Expo on Nanotechnology & Materials Science

5th World Congress & Expo on Nanotechnology & Materials Science will be held during September 27-28, 2021. Dubai |U.A.E. Scientific

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March 4, 2021 Drug delivery / Pharma applications

FDA Issues Emergency Use Authorization for Third COVID-19 Vaccine

As we reported on CDN blog FDA approval for Janssen vaccine containing HPBCD was expected in late February. The Janssen

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March 3, 2021 Drug delivery / Pharma applications

Improving Bioavailability & Solubility

Drug Development & delivery published on the virtual 2020 Global Drug Bioavailability Enhancement Summit, which this past December showcased novel

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Recent Posts

  • Registration opened for virtual abridged meeting prior to International Cyclodextrin Symposium
  • Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
  • Evading Thermodynamic Constraints of Cyclodextrin-Drug Formulations
  • Cyclodextrins in Antiviral Therapeutics and Vaccines
  • FDA granted accelerated approval to umbralisib / HPBCD tablet

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Top Posts

  • Registration opened for virtual abridged meeting prior to International Cyclodextrin Symposium
  • Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
  • Cyclodextrins in Antiviral Therapeutics and Vaccines
  • Evading Thermodynamic Constraints of Cyclodextrin-Drug Formulations
  • FDA granted accelerated approval to umbralisib / HPBCD tablet
  • The monograph of SBECD is official in the European Pharmacopeia
  • Nasal delivery with beta-cyclodextrin is approved; a short story of Baqsimi
  • How air fresheners work?
  • Host-guest chemistry for the treatment of leishmania
  • Reviews on cyclodextrin-metal-organic frameworks (CD-MOFs) in food applications

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