Phase III Results of Adamgammadex
We have previously reported about a potential new neuromuscular blockade reversal agent called adamgammadex. Its structure is quite similar to
Differences in the Intracellular Localization of Methylated β-Cyclodextrins-Threaded Polyrotaxanes Lead to Different Cellular States
Activation of autophagy represents a potential therapeutic strategy for the treatment of diseases that are caused by the accumulation of
Symposium of Drug Delivery Systems
The 11th Annual International Symposium of Drug Delivery Systems (SDDS-2024) will be held on May 22-24, 2024 in Osaka, Japan.
Anti-melanoma potential of inclusion complexes containing phyllacanthone in β-cyclodextrin and sulfobutyl-ether-β-cyclodextrin
The bis-nor-diterpene phyllacanthone (PHY) was isolated from the chloroform fraction of the stem barks from Cnidoscolus quercifolius Pohl (Euphorbiaceae). PHY/β-CD
Cyclodextrins: prospective nanocarriers for the delivery of antibacterial agents, against bacteria that are resistant to antibiotics
A review with 303 references Several different kinds of cyclodextrin nanocarriers (β-CD, HP-β-CD, Meth-β-CD, cationic CD, sugar-grafted CD) are utilized
Wasabi’s bioactive component 6-MSITC formulated with alfa-cyclodextrin improved memory proven in clinical trial.
6-(Methylsulfinyl)hexyl isothiocyanate (6-MSITC ) is the main bioactive compound of wasabi. A Japanese panel of scientists investigated the benefits of
An unprecedented example for sole cyclodextrins as API: an ophthalmic composition with hydroxypropyl betadex, alone
A paradigm shift in cyclodextrin technology started with the design, development and marketing of Sugammadex®/Bridion®, and followed by designation of
Chitosan and SBEBCD hydrogel for the treatment of bladder cancer
Implantable system maximizes drug concentration and continuously releases drugs near the tumor, which is an effective tool to solve the
Unraveling the interaction of drug (Diflunisal) with cyclodextrin and protein (Lysozyme) by fluorescence spectroscopy
Understanding the interaction between the drug:carrier complex and protein is essential for the development of a new drug-delivery system. However,
Stabilization effects of saccharides in protein formulations: A review of sucrose, trehalose, cyclodextrins and dextrans
Saccharides are a popular group of stabilizers in liquid, frozen and freeze dried protein formulations. The current work reviewed the
A prestigious award for studies of INACTIVE pharmaceutical ingredients (Ralph Shangraw Memorial Award)
University of Mississippi pharmacy professor, Michael Repka has been announced as recipient of the 2023 Ralph Shangraw Memorial Award. Professor