Enhancing Remdesivir Delivery: PJL Micelles vs SBECD Formulations
Remdesivir (REM), a nucleoside analogue that has been approved for SARS-CoV-2 treatment, is poorly soluble in water and is currently
Tag: drug delivery
Pharmaceutics 2027 conference
The Pharmaceutics 2027: From Biopharmaceutics to Clinical Pharmaceutics will take place in Barcelona, Spain from 28 to 30 June 2027. The following sessions are planned:
Revolutionary Nanozyme Microneedles for Gout Treatment
The Chinese group designed novel cyclodextrin-engineered bioinspired nanozyme (T-CD/Pt), and integrate it into a bi-regional microneedle (TP-MNs). Coupled with a
A “three-in-one” strategy for enhancing osteogenic, angiogenic and antibacterial properties of titanium implants
To enhance the bioactivity and antimicrobial properties of orthopedic Ti implants, a “three-in-one” coating was well designed and fabricated. A
Cyclodextrin-Based Formulations to Improve Solubility of Poorly Soluble Drugs
This chapter offers a detailed overview of the structural features, different types, and chemical modifications of CDs and their derivatives,
Disruption of Lipid Sorting and Endosomal Transport in Cyclodextrin-mediated Cytotoxicity
The effects of native and modified CDs in human renal proximal tubule cells was studied using complementary imaging, flow cytometry,
Reviewing Cyclodextrin-Grafted Polysaccharides as Sustainable Platforms for Biomedical and Environmental Applications
In this collaborative teamwork, the cyclodextrins (CDs) are reviewed as important building blocks for polymeric systems in biomedical and environmental
Dendronized βCD Molecular Containers for Enhancing Drug Delivery
Researchers from Mexico 🇲🇽 investigated dendronized βCD molecular containers designed to improve cellular uptake while maintaining biocompatibility. In human astrocyte
Cyclodextrin-Based Oral Solution of Ursodeoxycholic Acid Using a Ready-to-Use Vehicle
Researchers from Italy and Argentina developed a HPBCD-based oral solution of ursodeoxycholic acid (UDCA), a bile acid widely used for
Cholesteryl Cyclodextrin for Enhanced Delivery of Doxorubicin and 5-Fluorouracil
This study (1) aims to build on previously published results that characterized cholesteryl-modified β-cyclodextrin (CD21chol) as a carrier for 5-fluorouracil. (2)