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Category: CD derivatives

March 23, 2021 Analysis / CD derivatives / Drug delivery / Environmental / Food / Non-pharma applications / Other industrial use / Pharma applications

The story of cyclodextrin metal–organic frameworks and their applications from Nobel-prize laureate, F. Stoddart

Cyclodextrin-based metal–organic frameworks (CD-MOFs), derived from γ-cyclodextrin (γ-CD) and alkali metal cations, constitute a class of porous, renewable, and edible

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March 22, 2021 Analysis / CD derivatives / Drug delivery / Other industrial use

Review on cyclodextrin-based functional systems for biomedical applications

In this review Xu et al. (2021) highlight the characteristics and advantages of CDs as a starting point to design

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March 18, 2021 CD as API / CD derivatives / Pharma applications

First results on cyclodextrins against dengue fever from CycloLab

In May, 2020, CycloLab announced a collaboration, where University of California, Berkeley, Excivion and CycloLab teamed-up to evaluate the antiviral

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March 15, 2021 CD derivatives / Drug delivery / Pharma applications

Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery

Thiolated β-cyclodextrin (β-CD) has the potential to enhance mucoadhesive and permeation enhancing properties on ocular mucosa. Thiolated β-CD was synthesized via replacement

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March 8, 2021 CD as API / CD derivatives / Pharma applications

Polycationic cyclodextrin nanoparticles induce apoptosis and affect antitumoral activity

Hepatocellular carcinoma (HCC) is a highly metastatic primary liver cancer generating molecular alterations that end up escaping the apoptotic machinery

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March 2, 2021 CD derivatives / Drug delivery / Pharma applications

Heptakis(6-amino-6-deoxy)-beta-cyclodextrin stabilizes the synthetic anticoagulant fondaparinux

The intermolecular interactions between the cationic per-6-amino-b-CD with the highly anionic heparin analogue anticoagulant fondaparinux were studied at two different

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person holding syringe
February 25, 2021 CD derivatives / Pharma applications

HPBCD is a unique component in Janssen’s COVID-19 vaccine candidate

Amongst Janssen’s novel single-dose Covid-19 vaccine candidate of adenovirus platform excipients one might notice a peculiar compound: Hydroxypropyl Betadex (HPBCD).

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February 16, 2021 CD as API / CD derivatives

Gd(3+) Complexes Conjugated to Cyclodextrins

In the search for improvement in the properties of gadolinium-based contrast agents, cyclodextrins (CDs) are interesting hydrophilic scaffolds with high

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February 11, 2021 CD as API / CD derivatives / Pharma applications

Cyclo Therapeutics Presents Positive Data from Clinical Development Program for Lead Candidate, Trappsol® Cyclo™, at WORLDSymposium 2021

Cyclo Therapeutics, Inc., a clinical stage biotechnology company developing cyclodextrin-based products for the treatment of Niemann-Pick Disease Type C and

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February 3, 2021 CD derivatives

Ester-Bridged β-Cyclodextrin Nanosponges: Effect of the Cross-Linking Density

The cross-linking density influences the physicochemical properties of cyclodextrin-based nanosponges (CD-NSs) used for various purposes including drug delivery. Although the

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Recent Posts

  • Registration opened for virtual abridged meeting prior to International Cyclodextrin Symposium
  • Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
  • Evading Thermodynamic Constraints of Cyclodextrin-Drug Formulations
  • Cyclodextrins in Antiviral Therapeutics and Vaccines
  • FDA granted accelerated approval to umbralisib / HPBCD tablet

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Top Posts

  • Registration opened for virtual abridged meeting prior to International Cyclodextrin Symposium
  • Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
  • Cyclodextrins in Antiviral Therapeutics and Vaccines
  • Evading Thermodynamic Constraints of Cyclodextrin-Drug Formulations
  • FDA granted accelerated approval to umbralisib / HPBCD tablet
  • The monograph of SBECD is official in the European Pharmacopeia
  • Nasal delivery with beta-cyclodextrin is approved; a short story of Baqsimi
  • How air fresheners work?
  • Host-guest chemistry for the treatment of leishmania
  • Reviews on cyclodextrin-metal-organic frameworks (CD-MOFs) in food applications

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