Category: CD derivatives
Comparison of the siRNA and mRNA Carrying Capacity of Quaternary Ammonium β-Cyclodextrin Polymer and Polyethylenimine
The study investigates the effectiveness of a cationic cyclodextrin polymer-based delivery system for intracellular transport of RNA molecules. Efficient delivery
Poly-CD-PEG-camptothecin Combined with Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer (Clinical trial)
The authors hypothesized that integrating tumor-targeted topoisomerase I inhibitor delivery with optimized PARP inhibitor scheduling could enable effective combination therapy
Alkali Metal Adduct Formation in Cyclic Ion Mobility-Mass Spectrometry of O-Methylated Cyclodextrin Isomers
A recent study demonstrated how alkali metal adduct formation can significantly improve the analysis of O-methylated cyclodextrin isomers using cyclic
Cyclodextrin-based polymer materials and their applications – A review covering a 20-year period
Cyclodextrins (CDs) have undergone a remarkable evolution over the past three decades, transitioning from classical solubilizing agents to multifunctional platforms
Modifying the interior cavity of cyclodextrin
A collaboration between UCLA and the University of Hong Kong describes a method of using Quinuclidine as a catalyst to
Nano-Enabled Toxicity of Pharmaceutical Excipients
Nanotechnology has brought revolutionary advances in the pharmaceutical field. Among drug delivery systems, nanocarriers, which enhance the solubility, stability and
PEG-β-Cyclodextrin polymer-based formulation to increase the antiangiogenic activity of rutin in vivo
Rutin (RTN) is a natural flavonoid with well-documented anti-angiogenic, antioxidant, anti-inflammatory, and anti-cancer properties. However, its therapeutic potential is limited
Methyl salicylate/methyl-β-cyclodextrin inclusion complex modulates plant defense against cold and heat stress
Methyl salicylate (MeSA), a known defense modulator, holds promise as a biostimulant; however, its volatility and poor aqueous solubility limit