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Category: CD as API

January 5, 2026 CD as API / Pharma applications

2,6‑di‑O‑methyl‑3‑acetyl‑β‑cyclodextrin: a novel approach to reducde infectivity of SARS‑CoV‑2 and Japanese encephalitis virus

Among 19 CD derivatives studied, pretreatment of viral particles with DMA-β-CyD significantly reduced infectivity (by 2.25–2.67 log₁₀ units after 180

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December 26, 2025 CD as API / Drug delivery / Pharma applications

Neuroprotective effects of statins and cyclodextrins: review and potential role in dementia treatment

Dementia is a progressive and irreversible deterioration in cognition that has a significant impact on the person’s activities of daily

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December 23, 2025 CD as API / CD derivatives / Pharma applications

Multifunctional biomimetic nanocarriers for the treatment of atherosclerosis

Atherosclerosis (AS) has been considered a systemic disease characterized by the excessive generation of reactive oxygen species (ROS) and the

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a rat is standing on top of a plastic container
December 18, 2025 CD as API / CD derivatives / Pharma applications

Selective removal of 7-ketocholesterol by a CD-dimer, a novel atherosclerosis therapeutic candidate

The removal of the toxic oxidized cholesterol, 7-ketocholesterol (7KC), from cells through the administration of therapeutics has the potential to

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December 15, 2025 CD as API / CD derivatives / Pharma applications

Dual activity of low-molecular-weight polymeric β-cyclodextrins against tuberculosis

/The biological properties of pβCD of different molecular weights were studied. Strikingly, only the low-molecular-weight pβCD (LMW-pβCD) displayed antibacterial activity,

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December 11, 2025 CD as API / Pharma applications

Biomimetic cyclodextrin enzyme models for modulation of P. aeruginosa quorum sensing and host immune response

Quorum sensing (QS) is the cell-to-cell communication on cell density, which is based on signal molecules,  N-acyl-homoserine lactones (AHLs) for

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December 1, 2025 CD as API / CD derivatives / Drug delivery / Pharma applications

From an Idea to a Journey: My Path Toward Treating Gout and Hyperuricemia With Cyclodextrins

When I look back at the last few years, it’s hard not to feel moved by what this project has

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a rat is standing on top of a plastic container
November 24, 2025 CD as API / CD derivatives / Pharma applications

A β-cyclodextrin polymer reduces cholesterol accumulation and mitigates autophagy dysfunction in vitro and in a Niemann–Pick Type C animal model

Niemann–Pick disease type C (NPC) and Alzheimer’s disease (AD) are both characterised by cognitive decline and neurological impairment. In each

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November 19, 2025 CD as API / Pharma applications

Amitriptyline in reducing bronchoconstriction effects compared to methyl BCD

Bronchial asthma is a chronic inflammatory disease with rising prevalence worldwide. Apart from the immunological role of the tricyclic antidepressant

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November 17, 2025 CD as API / Pharma applications

Cyclodextrins as Active Therapeutic Agents: Beyond Their Role as Excipients

Cyclodextrins (CDs) have traditionally been recognized as excipients that enhance solubility and stability of drugs. However, growing evidence shows that

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  • Cyclodextrin complexation of selected tyrosine kinase inhibitors

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  • Appropriate Dosing of Sugammadex in Morbidly Obese Patients
  • Water-Soluble EDTA-Crosslinked Poly-β-Cyclodextrins as Ion-Complexing Drug Carriers.

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