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Tag: Cancer therapy

January 12, 2024 Drug delivery / Pharma applications

Thymoquinone-Sulfobutylether-β-Cyclodextrin Inclusion Complex for Anticancer Applications

Thymoquinone (TQ) is a quinone derived from the black seed Nigella sativa and has been extensively studied in pharmaceutical and

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December 19, 2023 CD as API / CD derivatives / Pharma applications

Mannose-methyl-β-cyclodextrin suppresses tumor growth by targeting both colon cancer cells and tumor-associated macrophages

Methylated β-cyclodextrin (MβCD) can extract cholesterol from lipid rafts and induce apoptosis in cancer cells by inhibiting activation of the

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November 23, 2023 Drug delivery / Pharma applications

Anti-melanoma potential of inclusion complexes containing phyllacanthone in β-cyclodextrin and sulfobutyl-ether-β-cyclodextrin

The bis-nor-diterpene phyllacanthone (PHY) was isolated from the chloroform fraction of the stem barks from Cnidoscolus quercifolius Pohl (Euphorbiaceae). PHY/β-CD

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November 17, 2023 Drug delivery / Pharma applications

Chitosan and SBEBCD hydrogel for the treatment of bladder cancer

Implantable system maximizes drug concentration and continuously releases drugs near the tumor, which is an effective tool to solve the

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October 23, 2023 Uncategorized

Controlled delivery of sildenafil by β-Cyclodextrin-decorated sulfur-doped carbon nanodots: a synergistic activation of ROS signaling in tumors overexpressing PDE-5

Fluorescent sulfur- and nitrogen-doped carbon nanodots (CDs) are zero-dimensional nanoparticles that mediate ROS production in cancer cells, displaying inherent anticancer

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October 13, 2023 Events

16th Annual World Cancer Congress

at The 16th Annual World Cancer Congress will be held at June 12-14, 2024 in the beautiful city of Budapest,

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September 26, 2023 Drug delivery / Pharma applications / Uncategorized

Cytotoxicity of 5-Fluorouracil- Loaded, β-Cyclodextrin-Tethered Metallic Copper Nanoparticles on Triple-Negative Breast Cancer Cells

Metal nanoparticles represent simple nanoscale structures that can be employed in drug delivery. The complication due to multiple elements in

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August 16, 2023 Drug delivery / Pharma applications / Supramolecular systems

Rationally designed multifunctional nanoparticles as GSH-responsive anticancer drug delivery systems based on host-guest polymers derived from dextran and β-cyclodextrin

Tumor proliferation and metastasis rely on energy provided by mitochondria. The hexokinase inhibitor lonidamine (LND) could suppress the activities in

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June 20, 2023 Drug delivery / Pharma applications / Supramolecular systems

Glutathione-depleted cyclodextrin pseudo-polyrotaxane nanoparticles for anti-inflammatory oxaliplatin (IV) prodrug delivery and enhanced colorectal cancer therapy

Oxaliplatin (Oxa) is the first-line chemotherapeutic drug for the treatment of colorectal cancer (CRC). However, long-term Oxa chemotherapy can induce

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May 3, 2023 Drug delivery / Pharma applications

Sulfobutyl ether β-Cyclodextrin-based supramolecular nanoparticles: pH-sensitive nanocarriers for the sustained release of anti-tumor drugs

In this work, pH-responsive nanoparticles based on sulfobutyl ether-β-CD (SBE7-β-CD) and cetylbenzyldimethylammonium chloride (HDBAC) were designed and prepared. The obtained

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  • Cyclodextrin complexation of selected tyrosine kinase inhibitors

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