Hydrogels for Cancer Immunotherapy
Cancer is a complex disease characterized by systemic dysfunction, necessitating a balance between therapeutic efficacy and safety. Immunotherapy is a
Tag: PEG
DDS for Dacarbazine by combining CD encapsulation with gold nanoparticles
Dacarbazine (DB) is an antineoplastic drug extensively used in cancer therapy. However, present limitations on its performance are related to
Cyclodextrin and folate functionalized polymer nanocarriers: Chain length dependent properties
A series of β-cyclodextrin and folate-tethered poly(ethylene glycol) with various spacer chain lengths, prepared and characterized using spectroscopic methods. The
Application of cyclodextrin/polyethylene glycol in blood-storage tools for liquid biopsy
In recent years, liquid biopsy has garnered considerable attention as a valuable diagnostic technology for cancer. An analysis target of
Poly(pseudo)rotaxanes formed by mixed micelles and α-cyclodextrin for drug delivery to the nail
This work aimed to develop water-based formulations for onychomycosis topical treatment using micelles of small pegylated surfactants associated with α-cyclodextrin
Twenty years of research on cyclodextrin conjugates with PAMAM dendrimers
Cyclodextrin (CD) conjugates with starburst polyamidoamine (PAMAM) dendrimer (CDEs), as a new type of polymer-based carriers, were first published in
Engineered cyclodextrin derivatives for spontaneous coating of highly porous metal-organic framework nanoparticles
Nanosized metal-organic frameworks (nanoMOFs) MIL-100(Fe) are highly porous and biodegradable materials that have emerged as promising drug nanocarriers. A challenging
HPBCD is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease
Niemann-Pick type C1 (NPC1) disease is a fatal neurovisceral disease for which there are no FDA approved treatments, though cyclodextrin
Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery
In the laboratory of C. M. O’Driscoll (University College Cork), an antibody targeted cyclodextrin-based siRNA delivery vector (CD.DSPE-PEGFab) was developed