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Tag: RAMEB

January 29, 2025 Drug delivery / Pharma applications

Aqueous eye drop formulations: Cyclodextrins as enabling excipients

Cyclodextrins are enabling pharmaceutical excipients that solubilize and stabilize drugs in aqueous formulations. Cyclodextrins possess very favorable pharmacokinetic and toxicological

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May 16, 2024 Drug delivery / Pharma applications

Cyclodextrin-assisted drug repositioning: The case of disulfiram

„The most fruitful basis for the discovery of a new drug is to start with an old drug.” (Sir James

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October 30, 2023 CD as API / Pharma applications

Cyclodextrins permeabilize DPPC liposome membranes: a focus on cholesterol content, cyclodextrin type, and concentration

Cyclodextrins (CDs) are known for their ability to extract lipid components from synthetic and biological membranes and therefore to induce

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July 28, 2022 Drug delivery / Pharma applications

Cellular Effects of Cyclodextrins: Studies on Caco-2 and HeLa Cells

In this work the cellular internalization and the intracellular effects of (2-hydroxypropyl)-beta (HPBCD) and random methyl-beta cyclodextrin (RAMEB) on Caco-2

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September 15, 2021 Environmental / Non-pharma applications

Cyclodextrin-based supramolecular low melting mixtures: efficient absorbents for volatile organic compounds abatement

Cyclodextrins (CDs) and deep eutectic solvents (DESs) are emerging absorbent materials for the removal of volatile organic compounds (VOCs). DESs

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August 25, 2021 Drug delivery / Pharma applications

Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

Quercetin, a flavonoid with possible neuroprotective action has been recently suggested for the early-stage treatment of Alzheimer’s disease. The low

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August 18, 2021 Food / Non-pharma applications

Cyclodextrins as high-performance green co-solvents in the aqueous extraction of polyphenols and anthocyanin pigments from solid onion waste

Three commonly used cyclodextrins (CDs), β-cyclodextrin (β-CD), methyl β-cyclodextrin (m-β-CD) and 2-hydroxypropyl β-cyclodextrin (HP-β-CD) were studied as green co-solvents for

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August 5, 2021 Drug delivery / Pharma applications

CD-complexation enhances in vivo anti-fibrotic and anti-inflammatory effects of chrysin

Chrysin (CHR) is a natural flavonoid with a wide range of pharmacological activities, including hepatoprotection, but poor water solubility. By

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August 2, 2021 Drug delivery / Pharma applications

Are cyclodextrins safe for intravitreal injections?

Cyclodextrins are excellent excipients for various routes of administration, the ophthalmic delivery is potentially one of the most useful applications

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July 12, 2021 Drug delivery / Pharma applications

Nanofibrous Formulation of Cyclodextrin Stabilized Lipases for Efficient Pancreatin Replacement Therapies

The purpose of enzyme therapies (ERT) is simple: patients who suffer from enzyme deficiency should be treated by administering enzymes

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Recent Posts

  • Comparative Study of Nanosuspensions for Acetogenins Delivery
  • Sustained transdermal delivery of insulin-cyclodextrin through the use of chitosan-based microneedle patches
  • Events of American Cyclodextrin Consortium
  • Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
  • Nano-Enabled Toxicity of Pharmaceutical Excipients

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Top Posts

  • Comparative Study of Nanosuspensions for Acetogenins Delivery
  • Sustained transdermal delivery of insulin-cyclodextrin through the use of chitosan-based microneedle patches
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
  • Dual function of sulfobutylether-betadex in antiviral Veklury®: a remdesivir solubilizer and an effector
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Lanosterol eye drops for cataract treatment
  • Comparative evaluation of lyophilized voriconazole formulations marketed in European Union
  • Nanotechnology World Conference 2026
  • Monosubstituted Maltosyl Cyclodextrins for the Potential Treatment of NPC

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