Complexation of cholesterol with β-cyclodextrin derivatives: A combined theoretical and experimental study
This study aimed to compare differences in interactions between cholesterol and β- cyclodextrin and its derivatives for selecting a suitable
Tag: methyl BCD
Cyclodextrins and Their Polymers Affect Human Serum Albumin’s Interaction with Drugs Used in the Treatment of Pulmonary Infections
Respiratory infectious diseases have challenged medical communities and researchers. Ceftriaxone, meropenem and levofloxacin are widely used for bacterial infection treatment,
Methyl BCD alters cell envelop studied by AFM
To elucidate the involvement of the cell envelope in the stiffness of sickle cells, methyl-β-cyclodextrin (MβCD), a putative cholesterol-depleting reagent
Dimethyl-α-cyclodextrin induces capacitation by removing phospholipids from the plasma membrane of mouse sperm
Dimethyl-alpha-CD (DMACD) was found to enhance sperm fertilization ability by removing phospholipids. It was concluded that in addition to the
Mannose-modified methyl-β-cyclodextrin suppresses tumor growth
Methylated β-cyclodextrin (MeβCD) can extract cholesterol from lipid rafts and induce apoptosis in cancer cells by inhibiting activation of the
Eye drops containing methyl BCD as active – clinical trial
Cloudbreak Therapeutics, LLC has sponsored a multicenter, randomized, double-masked, vehicle-controlled, parallel group study using CBT-008 (buffered solution of methyl BCD)
Targeting Lipid Rafts as a Strategy Against Coronavirus
Lipid rafts are functional membrane microdomains containing sphingolipids, including gangliosides, and cholesterol. These regions are characterized by highly ordered and
The use of β-CDs to improve honey bee health
Honey bees are essential members of the natural ecosystems and the modern agriculture, yet their colonies are collapsing worldwide. In
An antibody–supermolecule conjugate for cancer chemotherapy
In this study, antibody–supermolecule conjugates, consisting of a tumor-specific antibody and acid-labile polyrotaxane containing methylated b-cyclodextrin (Me-PRX), were designed to
Modulation of Plasma Membrane Composition and Microdomain Organization by methyl beta-CD in B16-F10 Mouse Melanoma Cells
The most interesting finding of Crui et al. in their recently published paper [1] for the readers of the Cyclodextrin