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Tag: HPBCD

February 19, 2026 CD as API / Drug delivery / Pharma applications

Enhancing the Water Solubility and Efficacy of Anticancer Drugs Using Hydroxypropyl-β-Cyclodextrin

Previous studies have demonstrated that the solubility and biocompatibility of poorly water-soluble anti-cancer agents can be improved by complexation with

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February 9, 2026 CD as API / Drug delivery / Pharma applications

CDs for Regulating Cholesterol Homeostasis in Atherosclerosis

The progression of atherosclerosis (AS) is strongly linked to lipid crystals accumulation caused by cholesterol metabolism disorders and the worsening

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February 4, 2026 CD as API / CD derivatives / Pharma applications

Studies on Sleep-Deprived Animals Reveal HPBCD’s Role in Restoring Normal Neuronal Function

A study published in Proceedings of the National Academy of Sciences (https://www.pnas.org/doi/10.1073/pnas.2523438123) suggests that lack of sleep harms the fatty insulation that

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February 3, 2026 CD derivatives / Life sciences

Studies on Sleep-Deprived Animals Reveal HPBCD’s Role in Restoring Normal Neuronal Function

A study published in Proceedings of the National Academy of Sciences (https://www.pnas.org/doi/10.1073/pnas.2523438123) suggests that lack of sleep harms the fatty

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January 14, 2026 Drug delivery / Pharma applications

Cyclodextrin-Driven Drug Deaggregation

The poor aqueous solubility of niclosamide (Nic), a drug with broad therapeutic potential beyond its original antiparasitic use, presents a

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January 9, 2026 CD as API / Pharma applications

Hydroxypropyl-Beta-Cyclodextrin (HPBCD) inhibits SARS-CoV-2 replication by modulating intracellular lipid dynamics

A multi-year scientific collaboration between Brasilian and American scientists from Federal University at Rio de Janeiro, Brazil, Laboratory of Immunoregulation,

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January 8, 2026 Drug delivery / Pharma applications

HPBCD in liquid formulations: a systematic study of physical properties and surfactant compatibility

The researchers of TEVA (USA) explored the role of 2-hydroxypropyl-β-cyclodextrin (HPβCD) as an excipient in liquid formulations by evaluating its

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December 26, 2025 CD as API / Drug delivery / Pharma applications

Neuroprotective effects of statins and cyclodextrins: review and potential role in dementia treatment

Dementia is a progressive and irreversible deterioration in cognition that has a significant impact on the person’s activities of daily

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December 23, 2025 CD as API / CD derivatives / Pharma applications

Multifunctional biomimetic nanocarriers for the treatment of atherosclerosis

Atherosclerosis (AS) has been considered a systemic disease characterized by the excessive generation of reactive oxygen species (ROS) and the

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December 22, 2025 Drug delivery / Pharma applications

HPBCD and polysorbate containing formulation to eliminate aggregation of a potent osteogenic protein, recombinant human NELL-1

This study utilized a four-stage rational formulation development approach to mitigate aggregation and stabilize a high molecular weight protein, rhNELL-1.

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Recent Posts

  • Cyclodextrin Produced In situ: Rethinking Oat Milk Design for Better Performance
  • Structural diversity of cyclodextrin metal-organic frameworks enables their diverse applications
  • Exploring Cyclodextrin-Based MOFs for Drug Delivery: Synthesis, Applications, and Future Perspectives
  • Sugammadex analog water soluble BCD polymer for peptide complexes
  • 2 nd International Conference on Biomedical Science and Engineering

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Top Posts

  • Cyclodextrin Produced In situ: Rethinking Oat Milk Design for Better Performance
  • Structural diversity of cyclodextrin metal-organic frameworks enables their diverse applications
  • Cyclodextrin-based formulations for pediatric patients: pharmaceutical prospectives and toxicological evaluation
  • Lanosterol eye drops for cataract treatment
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • FDA Grants Approval to HPBCD-Enhanced Biologic: A 'Super-Originator' Formulation
  • Antiepileptic drug with betadex sulfobutyl ether sodium, Fycompa® injection approved in Japan
  • "Advances in Functional Materials" International Conference, 2021
  • Alterations in Proteostasis Mechanisms in Niemann–Pick Type C Disease
  • Aequus and reVision to Collaborate on Stargardt Disease Program using SBECD as active

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