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Tag: HPBCD

January 9, 2026 CD as API / Pharma applications

Hydroxypropyl-Beta-Cyclodextrin (HPBCD) inhibits SARS-CoV-2 replication by modulating intracellular lipid dynamics

A multi-year scientific collaboration between Brasilian and American scientists from Federal University at Rio de Janeiro, Brazil, Laboratory of Immunoregulation,

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January 8, 2026 Drug delivery / Pharma applications

HPBCD in liquid formulations: a systematic study of physical properties and surfactant compatibility

The researchers of TEVA (USA) explored the role of 2-hydroxypropyl-β-cyclodextrin (HPβCD) as an excipient in liquid formulations by evaluating its

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December 26, 2025 CD as API / Drug delivery / Pharma applications

Neuroprotective effects of statins and cyclodextrins: review and potential role in dementia treatment

Dementia is a progressive and irreversible deterioration in cognition that has a significant impact on the person’s activities of daily

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December 23, 2025 CD as API / CD derivatives / Pharma applications

Multifunctional biomimetic nanocarriers for the treatment of atherosclerosis

Atherosclerosis (AS) has been considered a systemic disease characterized by the excessive generation of reactive oxygen species (ROS) and the

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December 22, 2025 Drug delivery / Pharma applications

HPBCD and polysorbate containing formulation to eliminate aggregation of a potent osteogenic protein, recombinant human NELL-1

This study utilized a four-stage rational formulation development approach to mitigate aggregation and stabilize a high molecular weight protein, rhNELL-1.

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November 25, 2025 Drug delivery / Pharma applications

Cyclodextrin-assisted drug delivery to Central Nervous System: Mavenclad™ for multiple sclerosis treatment

In a recent study, Professors Bodor and Buchwald review the use of cyclodextrin-enabled formulations to develop oral tablets of cladribine

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October 20, 2025 CD as API / Pharma applications

Cholesterol in the CNS: functions, recycling and remyelination

The central nervous system ( CNS) is increasingly recognized as a cholesterol-rich organ. While the brain accounts for approximately 5%

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October 13, 2025 CD as API / Pharma applications

JIC Venture Growth Investments Invests in Beren Therapeutics P.B.C. to Advance Innovative, Cyclodextrin-based Therapeutics

JIC Venture Growth Investments (VGI) announced that it has invested in Beren Therapeutics P.B.C. (“Beren Therapeutics”). Beren Therapeutics is developing

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October 8, 2025 Drug delivery / Pharma applications

Recently published studies on dimethyl beta-CD

All these studies utilize the high solubilizing effect of 2,6-di-O-methyl beta-cyclodextrin studying various model drugs. The compatibility, inclusion stability, and

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October 6, 2025 Drug delivery / Pharma applications

Cyclodextrin-based formulations for pediatric patients: pharmaceutical prospectives and toxicological evaluation

Pediatric drug development faces notable challenges due to age-related physiological differences, with limited approved formulations often leading to off-label or

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Recent Posts

  • Call for Chapters: Cyclodextrins for Next-Generation Electronics and Energy Storage
  • Call for Chapters: Cyclodextrins in Nutraceuticals 
  • Comparison of the siRNA and mRNA Carrying Capacity of Quaternary Ammonium β-Cyclodextrin Polymer and Polyethylenimine
  • Call for Chapters: Cyclodextrins in Phytomedicine
  • Poly-CD-PEG-camptothecin Combined with Olaparib  in People With Relapsed/​Refractory Small Cell Lung Cancer (Clinical trial)

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Top Posts

  • Call for Chapters: Cyclodextrins in Phytomedicine
  • Call for Chapters: Cyclodextrins in Nutraceuticals 
  • Poly-CD-PEG-camptothecin Combined with Olaparib  in People With Relapsed/​Refractory Small Cell Lung Cancer (Clinical trial)
  • Comparison of the siRNA and mRNA Carrying Capacity of Quaternary Ammonium β-Cyclodextrin Polymer and Polyethylenimine
  • Call for Chapters: Cyclodextrins for Next-Generation Electronics and Energy Storage
  • New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA
  • GRAS status of CD derivatives
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Citric acid cross-linked β-cyclodextrins: A review of preparation and environmental/biomedical application
  • A Cyclodextrin Surprise in a Japanese Supplement

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