Sickle cell anemia and cyclodextrins
(The very first report on the beneficial consequence of cyclodextrin-assisted cholesterol removal from red blood cell membranes.) Sickle cell anemia
Tag: HPBCD
Development of a nasal spray based on cyclodextrin/hydrophobically-modified hydroxypropyl-methyl cellulose for the prevention of viral respiratory infections
The work aims to develop mucoadhesive and thermo-responsive in situ gelling systems, using hydrophobically-modified hydroxypropyl-methyl cellulose (Sangelose, SG) and beta-cyclodextrin
Combining two drugs with two CDs for formulation of a dry powder for inhalation
Dry powders for inhalation are evolving to address the challenge of maximizing lung deposition, with growing interest in carrier-free formulations
Novel Ibuprofen/HP-β-CD Hydrogel for Enhanced Wound Healing Based on Oxidized Regenerated Cellulose
Preparation of the multifunctional IBU/HP-β-CD hydrogel: impeding bacterial growth, controlled drug dispensation, and enhancing wound healing A novel hydrogel system
Statins in Aqueous Cyclodextrin Ocular Preparations
Topical statin therapy holds promise for ocular diseases, such as age-related macular degeneration, but the effective delivery to the posterior
Novel insights from a quantitative analysis of cyclodextrin-induced ototoxicity in mice
The cochlea is vulnerable to various pathological conditions, with sensory cells typically being the primary targets of damage. However, supporting
HPBCD and SBEBCD as therapeutic agents for the treatment of ulcerative collitis
Ulcerative colitis (UC), a major subtype of inflammatory bowel disease (IBD) alongside Crohn’s disease, is characterized by a relapsing and
Cholesterol Depletion by Cyclodextrins Reduces Pain Sensation
The nociceptive Transient Receptor Potential Vanilloid 1 (TRPV1) and Ankyrin 1 (TRPA1) channels are predominantly expressed on peptidergic sensory nerves,
Advances in cyclodextrin-based materials: Anticancer and antimicrobial applications–A review (2021–2024)
This review explores the latest innovations in CD-based drug delivery, emphasizing their impact on both cancer treatment and antimicrobial strategies.
Does a Gut-Joint Axis exist? (Potential Role of bile acids and microbiome in Osteroarthritis treatment)
The gut-joint axis is a bidirectional communication and interaction between the gastrointestinal tract (gut) and the joints. It involves the