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Tag: HPBCD

February 19, 2026 CD as API / Drug delivery / Pharma applications

Enhancing the Water Solubility and Efficacy of Anticancer Drugs Using Hydroxypropyl-β-Cyclodextrin

Previous studies have demonstrated that the solubility and biocompatibility of poorly water-soluble anti-cancer agents can be improved by complexation with

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February 9, 2026 CD as API / Drug delivery / Pharma applications

CDs for Regulating Cholesterol Homeostasis in Atherosclerosis

The progression of atherosclerosis (AS) is strongly linked to lipid crystals accumulation caused by cholesterol metabolism disorders and the worsening

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February 4, 2026 CD as API / CD derivatives / Pharma applications

Studies on Sleep-Deprived Animals Reveal HPBCD’s Role in Restoring Normal Neuronal Function

A study published in Proceedings of the National Academy of Sciences (https://www.pnas.org/doi/10.1073/pnas.2523438123) suggests that lack of sleep harms the fatty insulation that

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February 3, 2026 CD derivatives / Life sciences

Studies on Sleep-Deprived Animals Reveal HPBCD’s Role in Restoring Normal Neuronal Function

A study published in Proceedings of the National Academy of Sciences (https://www.pnas.org/doi/10.1073/pnas.2523438123) suggests that lack of sleep harms the fatty

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January 14, 2026 Drug delivery / Pharma applications

Cyclodextrin-Driven Drug Deaggregation

The poor aqueous solubility of niclosamide (Nic), a drug with broad therapeutic potential beyond its original antiparasitic use, presents a

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January 9, 2026 CD as API / Pharma applications

Hydroxypropyl-Beta-Cyclodextrin (HPBCD) inhibits SARS-CoV-2 replication by modulating intracellular lipid dynamics

A multi-year scientific collaboration between Brasilian and American scientists from Federal University at Rio de Janeiro, Brazil, Laboratory of Immunoregulation,

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January 8, 2026 Drug delivery / Pharma applications

HPBCD in liquid formulations: a systematic study of physical properties and surfactant compatibility

The researchers of TEVA (USA) explored the role of 2-hydroxypropyl-β-cyclodextrin (HPβCD) as an excipient in liquid formulations by evaluating its

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December 26, 2025 CD as API / Drug delivery / Pharma applications

Neuroprotective effects of statins and cyclodextrins: review and potential role in dementia treatment

Dementia is a progressive and irreversible deterioration in cognition that has a significant impact on the person’s activities of daily

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December 23, 2025 CD as API / CD derivatives / Pharma applications

Multifunctional biomimetic nanocarriers for the treatment of atherosclerosis

Atherosclerosis (AS) has been considered a systemic disease characterized by the excessive generation of reactive oxygen species (ROS) and the

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December 22, 2025 Drug delivery / Pharma applications

HPBCD and polysorbate containing formulation to eliminate aggregation of a potent osteogenic protein, recombinant human NELL-1

This study utilized a four-stage rational formulation development approach to mitigate aggregation and stabilize a high molecular weight protein, rhNELL-1.

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Top Posts

  • BCD in starch-based composite active sheets for the preservation and packaging of blueberry fresh fruit
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  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
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  • 22nd International Cyclodextrin Symposium (ICS-22) in India
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  • A comparison of cyclodextrans, cyclodextrins, and their complexes
  • Wasabi's bioactive component 6-MSITC formulated with alfa-cyclodextrin improved memory proven in clinical trial.
  • Piroxicam/Cyclodextrin: 35 years on the market

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