Might cyclodextrin uptake mask antimicrobial activity?
Could excipients mask a bioactive effect? The team of López-Nicolás J.M. (University of Murcia, Spain) has recently published a curious
Tag: HPBCD
A HPBCD solubilized novel fusion inhibitor of influenza virus was found orally active in mice
A group of researchers employed by different subsidiaries of Janssen Research & Development, Scripps Research Institute, Department of Epidemiology, as well
Novel polyrotaxane for Niemann Pick disease type C treatment
The team of Gerhard Wenz (Saarland University, Germany) has published a novel polyrotaxane: hydroxypropyl-β-cyclodextrin(HPBCD):poly(decamethylenephosphate) which has several advantages over HPBCD
Antidepressant drug to treat sepsis
Sepsis is an often deadly complication of infection in which systemic inflammation damages the vasculature, leading to tissue hypoperfusion and
CTD Reports Initial Data for Two Clinical Trials of Trappsol® Cyclo™
CTD Holdings, Inc., a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical
CDs in biodegradation-based soil remediation under aerobic conditions
The non-toxic, biodegradable cyclodextrins (CDs) can solubilize poorly soluble organic contaminants such as PAHs, PCBs, chlorinated solvents, etc. via molecular
CTD Announces Partnership with United BioSource
CTD Holdings, a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical need,
CD-enabled elektrokinetic extraction of pollutants from soil
The electrokinetic extraction process removes metals and polar organic contaminants from low-permeability soil, mud, sludge, and marine dredging by applying
Cyclodextrins in veterinary medicine (Part 1)
It is well known, that cyclodextrins have many different applications. Can they be used in veterinary medicine? Well, yes and
FDA Approved Development of VAR 200 for Treatment of FSGS
Variant Pharmaceuticals, Inc received US Food and Drug Administration (FDA) has approval for the development of VAR 200 (2-hydroxypropyl-β-cyclodextrin, or