Cyclodextrin complexation of selected tyrosine kinase inhibitors
The comprehensive physicochemical characterization and cyclodextrin complexation of four tyrosine kinase inhibitors — erlotinib, gefitinib, vandetanib, and lapatinib — were
Tag: SBECD
SQ Innovation: FDA Approval for Lasix® ONYU, an At-Home Treatment for Edema in Heart Failure Patients
This second-generation delivery device provides a cost-efficient alternative to in-hospital treatment. Lasix® ONYU represents the most recent FDA-approved formulation incorporating
Cyclodextrin-based formulations for pediatric patients: pharmaceutical prospectives and toxicological evaluation
Pediatric drug development faces notable challenges due to age-related physiological differences, with limited approved formulations often leading to off-label or
Cyclodextrin-based therapeutics delivery systems: A review of current clinical trials
Cyclodextrins (CDs) and their polymers are gaining momentum as advanced drug delivery systems. A recent review (https://www.sciencedirect.com/science/article/pii/S2590257125000203) highlights their progress
Enhanced Solubility and Rapid Delivery of Vitamin D3 via Sulfobutyl Ether β-Cyclodextrin Inclusion Complex in Mouth-Dissolving Films
This study successfully demonstrates the preparation of a vitamin D3:SBE-BCD inclusion complex using an eco-friendly, microwave-assisted method that minimizes solvent
Cyclodextrins as Multifunctional Platforms in Drug Delivery and Beyond: Structural Features, Functional Applications, and Future Trends
This review outlines the structural features of native CDs and their chemically modified derivatives, emphasizing the influence of functionalization on
Allopregnalonone/SBECD Complex in Clinical Trial for Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in Post Traumatic Stress Disorder
Clinical trial NCT07079761 may help us understand treatable factors that increase risk for chronic or treatment-resistant Post Traumatic Stress Disorder
Statins in Aqueous Cyclodextrin Ocular Preparations
Topical statin therapy holds promise for ocular diseases, such as age-related macular degeneration, but the effective delivery to the posterior
Chiral electrokinetic chromatography using dual pseudo-stationary phases: SBE-β-CD with hydrophobic (deep) eutectic solvents versus micelles and ionic liquids
Two hydrophobic (deep) eutectic solvents (H(D)ESs), menthol:octanoic acid (Men:OctA) and menthol:trioctylphosphine oxide (Men:TOPO), were prepared, characterized, and then employed for
HPBCD and SBEBCD as therapeutic agents for the treatment of ulcerative collitis
Ulcerative colitis (UC), a major subtype of inflammatory bowel disease (IBD) alongside Crohn’s disease, is characterized by a relapsing and