SBECD, HPBCD and hydrophilic polymers to enhance the solubility of Benzthiazide, Isoxicam, and Piroxicam
The bioavailability of a drug depends, among other parameters, on solubility. One of the strategies used to enhance the solubility
Tag: SBECD
A comprehensive nomenclature system for cyclodextrins
Modified cyclodextrins (CDs) are cyclic oligosaccharides with many applications in drug delivery, catalysis, and as active pharmaceutical ingredients. In general,
SBECD-Enabled Environmentally Friendly UV Absorbers
Isoamyl 4-methoxycinnamate (IMC) is widely used in various fields because of its exceptional UV-filter properties. However, due to its cytotoxicity
Recent studies on dimethyl beta-CD
DIMEB (heptakis(2,6-di-O-methyl)-β-cyclodextrin, DMβCD (CYL-4668), was used for improving the solubility of Olmesartan medoxomil (OLM), the prodrug of olmesartan, an angiotensin II
Modified release and permeation of umifenovir with SBE-β-CD and polymer: Impact of biorelevant gastrointestinal fluids
In this study, solubility, dissolution and permeation processes of poor soluble antiviral anti-SARS-CoV-2 umifenovir (UMF) were improved with sulfobutylether-β-cyclodextrin (SBE-β-CD)
Cantrixil’s Career Shift: Orphan Drug Encapsulated in Alpha-Cyclodextrin Changes Hands (and Cyclodextrin)
On 31 March, 2025, Kazia Therapeutics (Australia) Announced sale of intellectual property and trademarks rights for Cantrixil, a product that
Electrospun poly-ε-caprolactone fibers loaded with inclusion complex of sulfobutyl ether β-cyclodextrin with dexamethasone as potential drug release systems
Electrospun poly-ε-caprolactone (PCL) fibers (mats) loaded with inclusion complex of sulfobutyl ether β-cyclodextrin sodium salt (SB-β-CD) with dexamethasone (Dex) were
Repurposing chlorpromazine for anti-leukaemic therapy with the drug-in-cyclodextrin-in-liposome nanocarrier platform
Acute myeloid leukaemia (AML), accounts for 30 % of adult leukaemia cases, predominantly affects individuals over 60. The standard “7 + 3” intensive
Oxidative Thermolysis of Sulfobutyl-Ether-Beta-Cyclodextrin Sodium Salt
This study investigates the spectral and PXR diffraction characterization of SBECD, its thermal stability profile, and decomposition mechanism using isoconversional
SBECD-dissolved Cemdomespib’s Effects on Neuromuscular Health in CMT1X Animal Model of Charcot–Marie–Tooth 1X Disease
Mutations in connexin 32 (Cx32) are a common cause of Charcot−Marie−Tooth 1X (CMT1X) disease, an inherited peripheral neuropathy characterized by