Rafael Holdings and Cyclo Therapeutics merge to advance Niemann-Pick drug as FDA rival decision nears
Rafael Holdings and Cyclo Therapeutics on Thursday announced a merger agreement as they look to spur development of their Niemann-Pick
Tag: Clinical trial
Gamma-cyclodextrin in herbal drinks with anti-aging and uric acid lowering effect
A randomized, double-blind controlled trial (NCT05986799) sponsored by Amway (China) was planned to start in August 2023 to study whether
The Use of Sugammadex as Rescue Therapy Following Inadequate Reversal With Neostigmine – Clinical trial
Neuromuscular blocking agents (NMBAs) are commonly used in the practice of anesthesiology for skeletal muscle relaxation to facilitate tracheal intubation,
Long-term administration of intravenous Trappsol® Cyclo™ (HP-β-CD) in Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial
Niemann-Pick disease type C (NPC) is a rare, fatal, pan-ethnic, autosomal recessive lysosomal storage disease characterized by progressive major organ
Midazolam/γ-cyclodextrin Premedication in Pediatric Anesthesia
ADV6209, a new formulation of midazolam with the addition of γ-cyclodextrin for oral use, has recently been licensed as the
Case Report: Severe SARS-CoV-2 Infection Treated with Remdesivir in a Patient with ESRD
Remdesivir has emerged as a promising antiviral drug against SARS-CoV-2. However, data regarding the clinical benefits of remdesivir in patients
First Patient Enrolled in Phase 1 Study of Midatech’s Panobinostat / HPBCD (MTX-110) for Recurrent Glioblastoma
Midatech Pharma PLC, an R&D biotechnology company focused on improving the bio-delivery and biodistribution of medicines, announced on 14 November
Positive postprandial glycaemic and appetite-related effects of wheat breads enriched with either α-cyclodextrin or hydroxytyrosol/α-cyclodextrin inclusion complex
A clinical trial in 2021 investigating the postprandial glycaemic and appetite-related effects of wheat breads enriched with either α-cyclodextrin or
Eye drops containing methyl BCD as active – clinical trial
Cloudbreak Therapeutics, LLC has sponsored a multicenter, randomized, double-masked, vehicle-controlled, parallel group study using CBT-008 (buffered solution of methyl BCD)
Safety, Immunogenicity of a Novel HPBCD-Adjuvanted Influenza Vaccine
A novel quadrivalent seasonal influenza vaccine (FluCyd-vac) adjuvanted with hydroxypropropyl-b-cyclodextrin (HP-β-CD) was found to be safe and immunogenic despite containing