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Tag: Clinical trial

February 12, 2024 Food / Non-pharma applications

Gamma-cyclodextrin in herbal drinks with anti-aging and uric acid lowering effect

A randomized, double-blind controlled trial (NCT05986799) sponsored by Amway (China) was planned to start in August 2023 to study whether

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July 26, 2023 CD as API / Pharma applications

The Use of Sugammadex as Rescue Therapy Following Inadequate Reversal With Neostigmine – Clinical trial

Neuromuscular blocking agents (NMBAs) are commonly used in the practice of anesthesiology for skeletal muscle relaxation to facilitate tracheal intubation,

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July 25, 2023 CD as API / Pharma applications

Long-term administration of intravenous Trappsol® Cyclo™ (HP-β-CD) in Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial

Niemann-Pick disease type C (NPC) is a rare, fatal, pan-ethnic, autosomal recessive lysosomal storage disease characterized by progressive major organ

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February 13, 2023 Drug delivery / Pharma applications

Midazolam/γ-cyclodextrin Premedication in Pediatric Anesthesia

ADV6209, a new formulation of midazolam with the addition of γ-cyclodextrin for oral use, has recently been licensed as the

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January 4, 2023 Drug delivery / Pharma applications

Case Report: Severe SARS-CoV-2 Infection Treated with Remdesivir in a Patient with ESRD

Remdesivir has emerged as a promising antiviral drug against SARS-CoV-2. However, data regarding the clinical benefits of remdesivir in patients

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November 16, 2022 CD derivatives / Drug delivery / Pharma applications

First Patient Enrolled in Phase 1 Study of Midatech’s Panobinostat / HPBCD (MTX-110) for Recurrent Glioblastoma

Midatech Pharma PLC, an R&D biotechnology company focused on improving the bio-delivery and biodistribution of medicines, announced on 14 November

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November 11, 2022 Food / Non-pharma applications

Positive postprandial glycaemic and appetite-related effects of wheat breads enriched with either α-cyclodextrin or hydroxytyrosol/α-cyclodextrin inclusion complex

A clinical trial in 2021 investigating the postprandial glycaemic and appetite-related effects of wheat breads enriched with either α-cyclodextrin or

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October 20, 2022 CD as API / CD derivatives / Pharma applications

Eye drops containing methyl BCD as active – clinical trial

Cloudbreak Therapeutics, LLC has sponsored a multicenter, randomized, double-masked, vehicle-controlled, parallel group study using CBT-008 (buffered solution of methyl BCD)

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September 2, 2022 Drug delivery / Pharma applications

Safety, Immunogenicity of a Novel HPBCD-Adjuvanted Influenza Vaccine

A novel quadrivalent seasonal influenza vaccine (FluCyd-vac) adjuvanted with hydroxypropropyl-b-cyclodextrin (HP-β-CD) was found to be safe and immunogenic despite containing

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August 19, 2022 Drug delivery / Pharma applications

Clinical trial: Allopregnalonone/Dexolve for Post Traumatic Stress Disorder

About 6.4% of the U.S. population suffers from posttraumatic stress disorder (PTSD). Trauma-focused psychotherapies are generally effective in PTSD, but

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  • Sugammadex analog water soluble BCD polymer for peptide complexes
  • 2 nd International Conference on Biomedical Science and Engineering
  • Sugammadex vs Neostigmine: Effects on Obese Patients’ Recovery
  • Cyclodextrin-Amino Acid Conjugates
  • Cyclodextrin complexation of selected tyrosine kinase inhibitors

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