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Tag: DIMEB

February 18, 2026 Drug delivery / Pharma applications

Dimethylated β-cyclodextrin inclusion complexes containing the guest steroid hormones progesterone and 17β-estradiol: syntheses, crystal structures, thermal analyses and steroid solubility enhancements

The aim of the present study was to complex the potent steroidal hormones progesterone (PRO) and 17β-estradiol (BES) with heptakis(2,6-di-O-methyl)-β-cyclodextrin

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January 20, 2026 Other industrial use

Cyclodextrins as Smart Additives to Boost Biosurfactant Production in Bacillus licheniformis

The growing demand for sustainable, biodegradable surfactants has pushed microbial biosurfactants—especially lipopeptides such as lichenysin—into the spotlight. Yet their industrial

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November 6, 2025 Non-pharma applications / Other industrial use

DIMEB for enhanced biosurfactant production in fermentaton

Biosurfactants are environmentally friendly alternatives for chemical surfactants and have a broad spectrum of applications in different industries such as

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October 8, 2025 Drug delivery / Pharma applications

Recently published studies on dimethyl beta-CD

All these studies utilize the high solubilizing effect of 2,6-di-O-methyl beta-cyclodextrin studying various model drugs. The compatibility, inclusion stability, and

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July 4, 2025 CD as API / CD derivatives / Drug delivery / Life sciences

Patent applications related to synthesis of heptakis(2,6-di-O-alkyl)-beta-cyclodextrin by CycloLab

45 years ago, Szejtli et al. reported on the synthesis of heptakis(2,6-di-O-methyl)-beta-cyclodextrin using dimethyl sulfate as alkylating agent in a

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May 29, 2025 Drug delivery / Pharma applications

Theoretical Calculation of the Solubility and Other Parameters for Poorly Water-Soluble Compounds from Binding Constants of Inclusion Complexes

Experimental determination of solubility is a time-consuming procedure with relatively high reagent consumption. The solubility of poorly water-soluble compounds in

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May 7, 2025 CD derivatives / Uncategorized

Rapid test for identification of heptakis (2,6-di-O-methyl) β-cyclodextrin in isomeric mixtures

A rapid test was worked out to identify single isomer heptakis(2,6-di-O-methyl) β-cyclodextrin (2,6-DIMEB), an isomer with distinct methylation pattern compared

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April 28, 2025 Drug delivery / Pharma applications

Recent studies on dimethyl beta-CD

DIMEB (heptakis(2,6-di-O-methyl)-β-cyclodextrin, DMβCD (CYL-4668), was used for improving the solubility of Olmesartan medoxomil (OLM), the prodrug of olmesartan, an angiotensin II

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July 3, 2024 Drug delivery / Pharma applications

Quercetin encapsulation in (2HP-β-CD)2 and (2,6Me-β-CD)2 complexes

Quercetin protects against many diseases due to its radical scavenging and anti-inflammatory properties. However, due to its poor bioavailability numerous

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June 14, 2024 Drug delivery / Pharma applications

Does Vinblastine Retain its Anticancer Effect in the Presence of Cyclodextrin? A Preliminary Study

In this work, investigating the synthesis and characteristics of cyclodextrin-vinblastine compositions, derivatives of the electroneutral DIMEB and the polyanionic SBECD

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Recent Posts

  • Comparative Study of Nanosuspensions for Acetogenins Delivery
  • Sustained transdermal delivery of insulin-cyclodextrin through the use of chitosan-based microneedle patches
  • Events of American Cyclodextrin Consortium
  • Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
  • Nano-Enabled Toxicity of Pharmaceutical Excipients

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Top Posts

  • Comparative Study of Nanosuspensions for Acetogenins Delivery
  • Polyphenols' encapsulation in cyclodextrins: An updated systematic literature review
  • Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
  • FDA Grants Approval to HPBCD-Enhanced Biologic: A 'Super-Originator' Formulation
  • Sustained transdermal delivery of insulin-cyclodextrin through the use of chitosan-based microneedle patches
  • Harnessing Organoid Platforms for Nanoparticle Drug Development
  • A review on sodium sulfobutylether-β-cyclodextrin (SBECD)
  • A new multi-compendia modified beta-cyclodextrin, Kleptose® HPB-LB parenteral grade
  • A sugammadex-analogue, per-6-O-carboxyhexyl-thio-gamma-CD (OKL-1111) is a highly potent and universal reversal agent for anticoagulants
  • New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA

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