Cyclodextrins applied for improved insulin therapy
A recently published patent application (US20210113666 – Systems, Methods and Products for Minimizing Tissue Reactions and Tissue Injury at an
Category: CD derivatives
Cyclodextrin dimers: a versatile approach to optimizing encapsulation and their application to therapeutic extraction of toxic oxysterols
A novel class of specifically engineered, dimerized cyclodextrin nanostructures was developed for the encapsulation of toxic biomolecules such as 7-ketocholesterol
Cyclo Therapeutics to Proceed with IND Filing for Phase 2 Trial Using Intravenous Trappsol® Cyclo™ in Alzheimer’s Disease
Cyclo Therapeutics, Inc., a clinical stage biotechnology company dedicated to developing life-changing medicines through science and innovation for patients and
Why HPGCD is better for NPC treatment compared to HPBCD?
Niemann-Pick disease type C (NPC) is a lysosomal storage disorder with disrupted intracellular cholesterol trafficking. HP-β-CD is a cholesterol solubilizer
CD derivative for sensitive quantification of carbon monoxide in vivo
Carbon monoxide (CO) is a gaseous molecule known as the silent killer. It is widely believed that an increase in
Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
Novel multifunctional drug delivery systems were developed by the Sortino’s group [1]. βCD-NBFNO1 and βCD-NBFNO2, covalently integrating an N-nitroso amino-nitro-benzofurazan
Evading Thermodynamic Constraints of Cyclodextrin-Drug Formulations
Drug Development and Delivery has published on excipients with the title: SPECIAL FEATURE – Excipients: Far From Inactive summarizing the
Cyclodextrins in Antiviral Therapeutics and Vaccines
The review of Braga et al. describes the various roles of cyclodextrins (CDs) in vaccines againstviruses and in antiviral therapeutics
FDA granted accelerated approval to umbralisib / HPBCD tablet
The Food and Drug Administration granted accelerated approval to umbralisib (Ukoniq, TG Therapeutics), a kinase inhibitor including PI3K-delta and casein
Encapsulation of menthol into cyclodextrin metal-organic frameworks
Cyclodextrin (CD)-metal-organic frameworks (MOFs) are developed as a new type of food-acceptable multi-porous material, which shows a great potential for